• AI-Generated Treatment Planning Algorithm Meets Real-World Medicine

    Clinical Reaserch News | One of the world’s largest cancer centers is believed to be the first to deploy artificial intelligence (AI) in a therapeutic capacity on real-world patients—specifically, for curative-intent radiation therapy treatment planning for prostate cancer. The methodology involves training an AI machine learning algorithm on previously treated patients to generate radiation treatments for new patients.

    Jun 24, 2021

  • Digital Patients Could Help More Drugs Reach Market

    Clinical Research News | Clinical trials employing digital representations of patients and running in parallel with actual clinical trials could soon help researchers understand what separates responders and nonresponders to a drug.

    Jun 23, 2021

  • How Duplicate Subjects in Clinical Trials Can Cripple Research Efforts

    Clinical Research News | There are many obstacles to successful and reliable clinical trials, however one challenge is often ignored: duplicate subjects in clinical trials. These individuals go by many names: “professional patients”, “professional study subjects”, and “duplicate subjects”. Their involvement and unscrupulous behavior greatly threaten the integrity of clinical trials.

    Jun 22, 2021

  • Digital Medication Adherence enables Data-Guided Feedback and Patient-Centered Clinical Trials

    Clinical Research News | While medication adherence has long been a measure of engagement with treatment in the healthcare setting, the metric has not, so far, been translated into the sphere of clinical research. It is time to embrace the combined power of digital health, smart devices and packaging, and data science to finally understand medication adherence, and use that knowledge to support participation in clinical trials.

    Jun 17, 2021

  • Gamifying Vision: How Mobile Gaming Is Tracking Vision Degradation in Patients

    Clinical Research News | Tilak Healthcare aims to combine video games with medical expertise so that the same vision monitoring tools that are reliable and useful for doctors will be playful and fun for users. If Tilak can achieve that, the company tools will be “sticky” enough to have a longstanding impact on the healthcare process for patients.

    Jun 16, 2021

  • The Intersection of Real-World Data and Machine Learning for Clinical Research

    Clinical Research News | Personalized medicine—as we use the term today—offers the promise of tailor-made treatment strategies for individual patients, but really personalized medicine is nothing new, said Jose-Felipe Golib-Dzib, project lead at Janssen R&D.

    Jun 15, 2021

  • Marking Our Agendas: SCOPE’s Clinical Research Leadership Forum

    Clinical Research News | Next month, the team behind SCOPE is launching a two-day leadership forum on clinical research. The event brings together an international group of clinical research innovators, trial designers, clin ops leaders, R&D heads and technologists to have real conversations about leadership in the rapidly changing world of clinical research.

    Jun 14, 2021

  • Electronic Health Record Well Suited For Pragmatic Clinical Trials

    Clinical Research News | A pair of clinical trials implemented through the Epic electronic health record (EHR) system were highlighted during a keynote address at the recent Colorado Pragmatic Research in Health Conference.

    Jun 10, 2021

  • Researchers Pragmatically Tapping Secondary Data Sources

    Clinical Research News | The benefits and challenges of leveraging secondary data for pragmatic research is growing based on to the reality that it takes 17 years for only 14% of research to translate into practice.

    Jun 9, 2021

  • The Practicalities Of Real-World Pragmatic Research

    Clinical Research News | The “explanatory-pragmatic continuum” was a major theme at this year’s Colorado Pragmatic Research in Health Conference. Speakers discussed the distinction between traditional clinical trials measuring efficacy of a drug in support of policy decisions and pragmatic ones looking at the effectiveness of interventions designed primarily to change the behavior of healthcare providers and patients.

    Jun 8, 2021

  • Decentralized, Virtual Trials Take the Day: Follow the Money

    Clinical Research News | Funding for streamlined decentralized trials and virtual research software solutions lead the funding in the clinical research space. Other big winners: a new preclinical fund and AI for various indications.

    Jun 3, 2021

  • The FDA Doesn’t Show Signs of Slowing Down – How Can Pre-Revenue Life Sciences Companies Keep Up?

    Clinical Research News | With the FDA working at a record pace, how can life sciences companies keep up and effectively move through the drug development life cycle? Answer: A robust technology solution that enables granular tracking of spending and scale as the as the company rapidly grows and moves through the four main stages of drug development: start-up, IPO, clinical trials, and commercialization.

    Jun 2, 2021

  • News from China, Europe-Based CROs, AI in Clinical Research, New Products

    Clinical Research News | University of Oxford launches a new Pandemic Sciences Centre, PPD opens China lab, IQVIA reports on R&D trends, research partnerships for AI in clinical research, and new products from TripleBlind.

    Jun 1, 2021

  • New PK Model Takes Some Of The Guesswork Out Of Pediatric Dosing

    Clinical Research News | A machine learning specialist in Finland is developing an algorithm for determining drug dosing in children at various stages of maturation, which could one day aid in the design of pediatric clinical trials having a small number of participants.

    May 27, 2021

  • Real-World Data Enhanced Clinical Trial Design

    Clinical Research News | The challenges associated with executing successful clinical trials are well documented and increasing. This reality prevents promising treatments from reaching patients faster. However, clinical research is evolving. The industry is seeing an unprecedented opportunity to improve the pace of new therapies to patients—especially those with life-threatening conditions—through novel applications of real-world data.

    May 26, 2021

  • How Clinical AI Can Help Improve Medication Adherence

    Clinical Research News | Medication can sometimes be a hard pill to swallow — just ask the estimated 50% of patients who don’t take their medication as prescribed. In the United States, it’s estimated that medication nonadherence accounts for up to 50% of treatment failures, around 125,000 deaths, and up to 25% of hospitalizations each year.

    May 21, 2021

  • Regulatory Strategy Needed To Keep Pace With COVID-Era Reforms

    Clinical Research News | The pandemic has put the spotlight on agencies around the world overseeing the conduct of clinical trials as well as advanced efforts to harmonize their separate sets of regulations. There has never been a better time to develop a regulatory strategy that factors in all the new moving parts and engages agencies early and often to stay on track.

    May 18, 2021

  • Tackling the Problem of Prescription Drug Diversion

    Clinical Research News | Although 9 in 10 patient care professionals handle prescription drugs responsibly, the 1 in 10 who steal and abuse them are putting themselves at mortal risk and forcing patients to endure untreated pain. Effective drug diversion prevention should be based on power artificial intelligence. Done right, drug diversion prevention powered by AI can save lives, improve patient care, reduce health care costs, and minimize wasted effort.

    May 14, 2021

  • Pragmatic Clinical Trials Need Their Own Set Of Rules

    Clinical Research News | Pragmatic clinical trials (PCTs) require a more nuanced playbook than traditional explanatory studies when it comes to informed consent and respect for individuals. New models for engagement, transparency, and accountability will also be needed to accommodate the scale and heterogeneity of PCTs.

    May 12, 2021

  • New ‘Research Data Mart’ To Help Academic Sites Track Trial Performance

    Clinical Research News | A university’s ability to conduct clinical trials with speed and efficiency has become a key consideration of the National Institutes of Health (NIH) when doling out grants, so the Medical University of South Carolina has created a digital platform called Research Integrated Network of Systems (RINS) to generate the kind of performance benchmarks that can help keep institutions in the running.

    May 10, 2021