• Management of Co-Occurring Conditions of Down Syndrome Becoming More Personalized

    Clinical Research News | Medical conditions vary widely in presentation, progression, and treatment response, with Down syndrome standing out as one of the most variable of all. The genetic occurrence, caused by an extra copy of chromosome 21, is widely considered one of the most heterogenous conditions, with highly variable clinical presentation from person to person.

    Aug 13, 2026

  • Blood Biomarker Panel May Enable Earlier ALS Prevention Trials

    Clinical Research News | Investigators at the University of Miami Miller School of Medicine reported that a 19-protein blood biomarker panel, which includes neurofilament light chain (NfL), accurately predicted the transition from presymptomatic disease to clinical amyotrophic lateral sclerosis (ALS), known as phenoconversion, across timeframes ranging from six months to five years.

    Aug 12, 2026

  • Primary Care Research Alliance ‘Flips the Script’ on Site Feasibility

    Clinical Research News | In the U.K., adversity has brought together 180 clinical trial sites—mostly GP (general practitioner) practices but also community health trusts, hospices, and home care providers—to realize that they have more to gain as collaborators than competitors. The mindset shift prompted the formation of the Primary Care Research Alliance (PCRA), which in the space of 18 months has grown from a core group of 12 practices with 250,000 patients to a network representing 8.5 million and counting.

    Aug 11, 2026

  • The Scope of Things: Chinese Drug Developers Look Toward Global Market

    Clinical Research News | In the most recent episode of The Scope of Things podcast, Daphne Smyth, head of global regulatory programs at Veristat, joins the conversation to relay her three days at BioChina 2026 in Suzhou and what the North American and European markets can expect from Chinese drug development.

    Aug 6, 2026

  • Vaccine ‘Intercepts’ Pancreatic Cancer in High-Risk Populations

    Clinical Research News | Fresenius expands its access to innovation networks through its own corporate venture capital fund; Draig accelerates pipeline of highly specific AMPA and GABAA receptor modulators; and more.

    Aug 4, 2026

  • Fresh Insights on What Helps Patient Recovery in the ICU

    Clinical Research News | The findings of more than 150 randomized controlled trials provide ample evidence that early mobilization of patients with acute respiratory failure (ARF) in the intensive care unit (ICU) is both safe and beneficial. Surprisingly, also giving them extra protein—a strategy used successfully with frail and elderly patients—doesn’t appear to have any additive benefit.

    Jul 30, 2026

  • Follow the Money: Metastatic Prostate Cancer, Once-Weekly GLP-1 Patch, Molecule Arts Platform

    Clinical Research News | Fresenius expands its access to innovation networks through its own corporate venture capital fund; Draig accelerates pipeline of highly specific AMPA and GABAA receptor modulators; and more.

    Jul 29, 2026

  • Flatiron Health UK, NHS Greater Glasgow and Clyde New Partnership, Acrosian’s Next-Gen Biometrics CRO, Spatial Biology in Clinical Research

    Clinical Research News | Parhelia Biosciences and Sirona Dx announce a strategic partnership; The University of Cincinnati and UC Health launched the Center for Alzheimer's and Neurodegenerative Diseases Research; and more.

    Jul 28, 2026

  • Now Enrolling: Massive Remote Study Tracking How the Brain Ages

    Clinical Research News | In the future, it may be possible for the physiological signals passively collected by a smartwatch to alert the wearer of a potential change in their cognitive state. Consumer electronics giant Samsung, for its part, has teamed up with the Neuroscape Center at the University of California San Francisco (UCSF) to explore the possibility of expanding the health- and fitness-tracking capabilities of its Galaxy Watch to assess functioning of the brain.

    Jul 23, 2026

  • Anthropic Announces Rare Disease Research Claude Grants

    Clinical Research News | Anthropic yesterday announced a focused call for applications for work on rare genetic diseases. Accepted applicants will receive up to $50,000 in Claude credits over six months, with the goal of building a community of researchers looking into how AI can reshape our understanding of rare disease.

    Jul 21, 2026

  • 3 Tips for a Lean and Efficient Clinical Data Management Function

    Clinical Research News | The landscape of clinical data management (CDM) is becoming increasingly complex. As a BCG report notes, sponsors’ expectations are rising. They are looking for greater consistency in speed and quality, better technology, and improved implementations.

    Jul 17, 2026

  • Coming Soon: One-time Treatment for Debilitating Genetic Condition

    Clinical Research News | Patients with hereditary angioedema have reason to be optimistic that regulatory approval of a one-time, in vivo CRISPR gene-editing therapy for the sudden and severe swelling attacks associated with the rare genetic condition could come as early as next year. Lonvoguran ziclumeran (lonvo-z), as it is known, has been under development by Intellia Therapeutics for the past six years.

    Jul 15, 2026

  • AI Eye Imaging Model Could Accelerate Clinical Trials and Drug Development

    Clinical Research News | An experimental artificial intelligence (AI) model called OCTCube-M could help improve patient selection, predict disease progression, and streamline clinical trials by extracting new insights from three-dimensional optical coherence tomography (OCT) eye scans.

    Jul 14, 2026

  • The Scope of Things: Scaling AI Agents In Clinical Trials

    Clinical Research News | Artificial intelligence agents are beginning to reshape clinical trial operations, but sponsors are still hesitating. Raj Indupuri, CEO of eClinical Solutions, joined the latest episode of The Scope of Things, hosted by Deborah Borfitz, to break down the three main obstacles hindering AI adoption: data readiness, governance and trust, and operating model change.

    Jul 9, 2026

  • Insilico Medicine Launches Phase III Trial for AI-Developed Drug

    Clinical Research News | Insilico Medicine is launching a phase III clinical program for rentosertib, its potentially first-in-class oral small-molecule inhibitor of TNIK (TRAF2- and NCK-interacting kinase) for the treatment of idiopathic pulmonary fibrosis (IPF), a progressive, age-related fibrotic lung disease with high unmet medical need. It is the next step in making AI-discovered drugs a reality for patients.

    Jul 8, 2026

  • Follow the Money: Liver Cell-Reprogramming Therapy, Full-Length Dystrophin Trial, Next-Gen Neuroplastogen

    Clinical Research News | cAMPfield is launching a global phase 2b trial for moderate-to-severe ulcerative colitis and a global phase 2 for Crohn’s disease; Gero intends to advance a portfolio of both disease-modifying and aging-slowing programs in parallel; ClearNote Health continues commercial clinical study execution and broader global access; and more.

    Jul 1, 2026

  • Restoring American Leadership in Clinical Trials, University of Texas MD Anderson Joins Global Consortium, Medable’s DDF Agent

    Clinical Research News | The Ellison Medical Institute enters an exclusive license with UniQuest; TrialAssure and Cancer Research UK’s Centre for Drug Development announce new partnership; EndoDNA launches BIOS, a clinical decision-support; and more.

    Jun 30, 2026

  • India Can Surpass China in Global Pharma. But Not Where Most People Think.

    Clinical Research News | India has long been called the pharmacy of the world. That reputation was earned through manufacturing scale, generics leadership, and the ability to supply medicines globally at extraordinary volume. But the next chapter for India’s pharmaceutical industry will be different. Recent industry discussion about India’s pharmaceutical ambitions has largely explored one question: Can India compete with China as a global pharmaceutical power?

    Jun 26, 2026

  • Novo Nordisk Clinical Trial Data Targeted in Data Attack

    Clinical Research News | In mid-June Novo Nordisk announced, “an IT security incident involving unauthorized access to a limited number of internal IT systems” that exposed personal information for clinical trial participants. Novo Nordisk listed the exposed data categories as Patient ID (random alphanumeric string) and information on trial participation; sex; year of birth; biomarkers; health/immunogenicity data; and lifestyle factors including smoking, alcohol use, and BMI.

    Jun 23, 2026

  • Moving from Active to Autonomous TMF with Agentic AI

    Clinical Research News | For years, TMF leaders advocated for active TMF, a model where the TMF is a "place to go to do your work" instead of a passive archive. The shift to active TMF made significant progress for life sciences, moving toward applications that deliver real-time trial execution and TMF management. With the introduction of agentic AI in clinical trials, TMF management is now evolving from active to autonomous.

    Jun 18, 2026