• Follow the Money: AI Drug Design Engine Development, Multiple Myeloma Trials, More

    Clinical Research News | Isomorphic Labs continues to develop its AI drug design engine; CellCentric advances in multiple myeloma; and more.

    May 26, 2026

  • Data is Both the Fuel and Downfall of AI in Drug Development

    Clinical Research News | High-impact opportunities for leveraging AI across the pharmaceutical R&D cycle are too numerous to count but won’t “automagically” solve any of the longstanding problems in ushering molecules to market. AI requires human attention to match tools to tasks for ensuring the accuracy of model predictions, and the pitfalls are dangerously easy to miss, according to a Novo Nordisk presentation at this week’s Scope X conference in Boston.

    May 21, 2026

  • Bacteria: Unsung Players in the Tumor Microbiome

    Clinical Research News | How cancer patients will respond to treatment can be anticipated based on their genetics as well as the tumor microenvironment, although one relevant component is often all but dismissed: the tumor microbiota. This is despite an abundance of evidence that a cancer’s microbial community plays a major role not only in therapeutic effects but also in tumor development, progression, and metastasis formation.

    May 20, 2026

  • FDA Conversation on Selective Safety Data Collection

    Clinical Research News | Earlier this month, TransCelerate BioPharma released a summary report focused on selective safety data collection (SSDC) gathered during a joint tabletop exercise convened in late 2025 in collaboration with U.S. Food and Drug Administration's (FDA) Center for Drug Evaluation and Research (CDER) Center for Clinical Trial Innovation (C3TI).

    May 19, 2026

  • 23andMe: How Genetics Contribute to GLP-1 Drug Outcomes

    Clinical Research News | An engaged research cohort of over 11 million genotyped individuals has enabled 23andMe to produce a library of more than 300 peer-reviewed publications over the past 16 years. Following a 2025 bankruptcy filing, when it reemerged as a nonprofit medical research organization, the focus has settled on providing individuals with access to their genetic information, supporting genetics education, and studies that provide a deeper understanding of human genetics.

    May 13, 2026

  • AI Framework for Differentiating Neurodegenerative Diseases

    Clinical Research News | A team of computational scientists at Lund University (Sweden) have built a deep, joint-learning proteomics model for improving the diagnostic accuracy for a handful of dementia-related conditions which in primary care settings remains challenging due to a shortage of informative biomarkers. Predicting these different but correlated pathologies together with a single blood test would facilitate a differential diagnosis with speed and confidence.

    May 12, 2026

  • Strengthening Patient Recruitment Through Smarter Trial Design

    Clinical Research News | Patient recruitment remains one of the most persistent bottlenecks in clinical research. Issues such as increasing protocol complexity, competition for eligible participants, and growing expectations around diversity are placing ever-greater pressure on study timelines. However, recruitment challenges are often a symptom of earlier decisions; when protocol feasibility is misjudged, or patient realities are not fully considered, recruitment delays become inevitable.

    May 8, 2026

  • The Scope of Things: Bridging Health Equity in Clinical Research

    Clinical Research News | Among the shifting tides around DEI, people are finding creative ways to keep the momentum going for equitable clinical trials. Ramona Burress, co-founder of Onyx Health Collective, and Cassandra O’Neal, founder of Illuminated Arc Consulting, discuss a practical look at health equity in clinical trials in the latest episode of The Scope of Things.

    May 6, 2026

  • Much Progress Needed Planning Research to Consider Sex as a Biological Variable

    Clinical Research News | In 2016, the National Institutes of Health (NIH) introduced a policy requiring grantees to consider sex as a biological variable in their experimental design, analyses, and reporting. Now a team from Northwestern University has assessed progress, highlighting significant room for improvement.

    May 5, 2026

  • Follow the Money: AKT1-Selective Inhibitors, Vision Restoration Treatments, Neurology and Neuropsychiatric Treatments

    Clinical Research News | Terremoto Biosciences advances lead AKT1-selective inhibitor programs through phase 1 clinical development; Ray Therapeutics provides support of late-stage clinical development and commercial readiness for the company’s lead program in retinitis pigmentosa; Tortugas advances its two lead candidates; and more.

    Apr 30, 2026

  • FDA Piloting Real-Time Review of Clinical Trial Data From AstraZeneca, Amgen

    Clinical Research News | The U.S. Food & Drug Administration is piloting real-time review of data from AstraZeneca and Amgen clinical trials, both using Paradigm Health's Study Conduct platform, and has issued a call for feedback on how artificial intelligence (AI)-enabled technologies can improve efficiency, speed, and quality of decision-making in early phase clinical trials. FDA has already received and validated signals for AstraZeneca’s trial and expects this to be the first step in implementing real-time clinical trials (RTCT).

    Apr 29, 2026

  • Discovery Life Sciences, Mindpeak Partnership, Streamlining Communications, Rare Disease Referrals

    Clinical Research News | Discovery Life Sciences and Mindpeak enter a partnership; Cenevo has launched the Labguru Customer Portal; myTomorrows and Rare Disease Research team up; and more.

    Apr 28, 2026

  • Lung Cancer Trial Trends Show Geographic Concentration

    Clinical Research News | In research presented this week at the American Association for Cancer Research (AACR) Annual Meeting, trends surfaced showing that between 2020 and 2024, the number of unique sites in the United States where phase I clinical trials for non-small cell lung cancer (NSCLC) were conducted decreased by 44% and became increasingly concentrated at the top 20 highest‑volume clinical trial sites largely located in major cities.

    Apr 23, 2026

  • Pistoia Alliance Furthers Research on Using Social Media Listening in Drug Discovery, Clinical Research

    Clinical Research News | In an expansion of its advocacy work into clinical fields, the Pistoia Alliance has launched new patient research to shape the ethical use of social media listening in drug development. The work is part of its ongoing Social Media Real-World Evidence (RWE) project.

    Apr 22, 2026

  • Veristat Discovers a Goldmine of Opportunities in China

    Clinical Research News | Following an eye-opening experience at China’s largest biotechnology and life sciences event, Veristat is positioning itself as a first mover in accommodating the regulatory needs of multiple Chinese companies eager to enter European and North American markets. The shift comes in response to government policy reforms over the past decade, with purpose-built R&D cities and science parks in more recent years acting as physical accelerators.

    Apr 16, 2026

  • Cautious Optimism About FDA’s One Pivotal Trial Policy

    Clinical Research News | Earlier this year, the U.S. Food and Drug Administration (FDA) made a single pivotal clinical trial the default requirement for getting a medicine to market in lieu of the traditional two-trial mandate. It was a controversial move designed to reduce clinical development costs for drug sponsors, but it comes with the peril of potential project failure if study results aren’t rigorously defensible—or if companies fail to invest heavily in the quality of that single trial using readily accessible tools for data monitoring, artificial intelligence (AI), and biosimulation.

    Apr 14, 2026

  • AI in the Clinical Space: What 2030 Looks Like

    Clinical Research News | Clinical research is entering a phase where “using AI” is no longer the headline, and redesigning clinical operations becomes the real work. Mike Sullivan, head of IT globally for development operations at Bristol Myers Squibb, joins The Scope of Things to discuss a persistent industry problem: clinical insight latency, the long delay between data being generated at sites and meaningful decisions being made by sponsors.

    Apr 9, 2026

  • AI Tool Adding Speed and Diversity to Cleveland Clinic Trials

    Clinical Research News | At Cleveland Clinic, a “medically trained” AI system is patient-finding for clinical trials, eliminating the tedium of manual chart reviews for sponsors and investigators requesting digital assistance. Synapsis AI, a Dyania Health technology, was vetted for the job and initially deployed at Cleveland Clinic’s Taussig Cancer Center and its Heart, Vascular and Thoracic Institute.

    Apr 8, 2026

  • Managing Metastatic Cancer: A Matter of Degree

    Clinical Research News | Cancer recurrence is a significant health issue and a major concern for survivors but could potentially be transformed into a manageable chronic condition with the advent of a magnetic nanoparticle hyperthermia system developed by the Israeli startup New Phase and newly installed at the Mayo Clinic last December. The novel technology uses iron oxide-containing nanoparticles that amass in tumors, which are then heated by an electromagnetic field to destroy them.

    Apr 7, 2026

  • Continuous Clinical Trials: History, Hype, and How to Make Them Work

    Clinical Research News | Food and Drug Administration Commissioner Marty Makary has been signaling a potential change to how clinical trials are conducted. Since assuming the Commissioner role, he has championed "continuous trials"  to accelerate drug development, calling the current phased approach inefficient.

    Apr 3, 2026