• piRNA Blood Test Opens New Pathways for Longevity

    Clinical Research News | A simple blood test built on a handful of small RNA molecules could reshape how researchers study aging and predict survival. Led by Virginia Byers Kraus, M.D. Ph.D., professor in the departments of medicine, pathology, and orthopedic surgery at Duke University School of Medicine, a team of researchers identified piwi-interacting RNAs (piRNAs) as powerful and potentially causal predictors of mortality in older adults.

    Mar 31, 2026

  • Blood Biomarker “Clock” Detects Alzheimer’s Symptoms

    Clinical Research News | Researchers from the Foundation for the National Institutes of Health, Washington University in St. Louis, the University of California San Francisco, the University of Wisconsin-Madison, and other collaborators found that a plasma biomarker—the ratio of phosphorylated to non-phosphorylated plasma tau at position 217, written %p-tau217—can be used to construct a “clock model” that can predict when Alzheimer’s disease symptoms appear.

    Mar 26, 2026

  • Follow the Money: Brain-Computer Retinal Implant Trial Results, Alzheimer’s Platform Development, More

    Clinical Research News | Science Corporation’s PRIMA trial results are featured in The New England Journal of Medicine and on the cover of Time; Cognito Therapeutics continues to clinically develop their Spectris platform; and more.

    Mar 25, 2026

  • Verily, Samsung Partnership, Scite MCP Improves AI Trustworthiness, Johnson & Johnson Receives FDA Approval

    Clinical Research News | Verily Life Sciences and Samsung Electronics America enter a collaboration; Research Solutions launches Scite MCP; Johnson & Johnson receives approval from FDA for TECVAYLI and DARZALEX FASPRO; and more.

    Mar 24, 2026

  • Is Agentic AI The ‘Next Leap Forward’ for Clinical Trial Data Management?

    Clinical Research News | In clinical trials, every second counts, both for patient outcomes and sponsor ROI. As data volumes grow and oversight expectations tighten under frameworks like ICH E6(R3), teams are being asked to do more, faster and with greater precision. It is no surprise then that agentic AI, which promises to deliver efficiencies far beyond previous models, is the current hot topic across the industry.

    Mar 20, 2026

  • The Brain’s Role in High Blood Pressure

    Clinical Research News | Hypertension, also known as high blood pressure, has long been thought of as primarily a disorder of the heart, kidneys, or blood vessels. A growing body of evidence suggests that, in a substantial proportion of patients, the condition originates in the brain.

    Mar 17, 2026

  • Clinical Operations in 2030: What Will It Look Like?

    Clinical Research News | Clinical Operations is entering a phase where the hype around artificial intelligence (AI) and digital transformation is giving way to something more meaningful. For the last decade, much of the industry’s effort has focused on layering new technologies onto existing processes. By 2030, that approach will no longer be enough.

    Mar 13, 2026

  • Smarter Study Designs to Improve Pediatric Rare Disease Trials

    Clinical Research News | Efforts to improve clinical trials for children with rare diseases must focus on ensuring flexibility while capturing the best data. Florence Mowlem, chief scientific officer at uMotif, joins the most recent episode of The Scope of Things to discuss how thoughtful study design—not just advanced technology—is essential for ensuring reliable data and strong patient participation.

    Mar 12, 2026

  • DECODE Initiative Seeks More Meaningful Endpoints for Obesity Drugs

    Clinical Research News | As the obesity drug market accelerates, clinical trial design is coming under renewed scrutiny, with growing pressure on sponsors to demonstrate benefits that extend beyond weight loss. The Digital Endpoint Collaboration for Outcomes Development (DECODE) Obesity initiative and cross-industry consortium, led by Ametris, is looking to validate new clinical outcome measures that capture how patients function and feel while on treatment.

    Mar 10, 2026

  • Rethinking Data Delivery in Clinical Research: Building Scalable, Secure, And Site-Centric Architectures

    Clinical Research News | In the era of decentralized trials and global research networks, the way we manage and deliver clinical data is undergoing a profound transformation. Historically, sponsors relied on manual processes and physical media—USB drives, CDs—to transfer essential trial data to investigator sites at study close-out.

    Mar 6, 2026

  • Medication Adherence Pill Could Solve Dire Healthcare Problem

    Clinical Research News | Medication nonadherence is a major, longstanding problem in healthcare, with the World Health Organization estimating 50% of patients with chronic diseases are not taking their drugs as prescribed. But MIT engineers are working to solve the problem with an ingestible and bioresorbable RFID-based sensor system, dubbed SAFARI, designed to safely and accurately monitor medication ingestion.

    Mar 3, 2026

  • New CEO of Sanofi, SEQSTER’s Harmonization Engine, Flatiron’s First Prostate Cancer Panoramic Datasets

    Clinical Research News | Sanofi appoints Belén Garijo as chief executive officer; SEQSTER launches 1-Click Data Refinery; Flatiron Health announces their first Panoramic datasets in the U.K. and Germany for patients with prostate cancer; and more.

    Feb 26, 2026

  • Follow the Money: Musculoskeletal Disease Trials, “Regulator-Ready Protocols” for Clinical Trials, More

    Clinical Research News | Angitia Biopharmaceuticals focuses on postmenopausal osteoporosis, osteogenesis imperfecta, and spinal fusion; Biorce’s clinical trial platform rolls out; and more.

    Feb 25, 2026

  • In an Ecosystem of Trust, Trial Enthusiasm can ‘Spread Like Wildfire’

    Clinical Research News | Ensuring that patients who participate in clinical trials are the ones who bear the burden of the disease is a major and well-recognized challenge due to barriers ranging from mistrust of research and science to lack of access to clinical trials and cultural and logistical barriers.

    Feb 19, 2026

  • Deloitte Survey Reveals Sharp US-International Split in Executive Sentiment as AI and R&D Productivity Take Center Stage

    Clinical Research News | Life sciences executives remain cautiously optimistic about 2026, but a striking geographic divide has emerged that reveals growing concerns about U.S. regulatory and pricing policies, according to Deloitte Consulting’s 2026 Life Sciences Executive Outlook. Andy Bolt, leader of the firm’s Life Sciences R&D Practice, presented the data earlier this month at the Clinical Trial Venture, Innovation, and Partnering event with SCOPE.

    Feb 24, 2026

  • Confronting the Challenges in Keeping Trials on Track

    Clinical Research News | A top scientific leader at Merck issued a call to action to stakeholders in the clinical research enterprise at last week’s SCOPE event, inviting them to focus on what’s important to the real-world people they’re looking to treat and clearly answering the questions being asked by people holding anti-science views.

    Feb 17, 2026

  • Pharma’s AI Adoption: Learning From Other Technology Adoptions

    Clinical Research News | At the recent SCOPE Venture, Innovation, and Partnering Conference in Orlando, healthcare veteran Carolyn Magill, Venture Partner at Defined Ventures, sat down with Sunny Kumar, Partner at Informed Ventures, to discuss a pressing question facing the pharmaceutical industry: How can pharma harness the transformative power of artificial intelligence while navigating its traditionally risk-averse culture?

    Feb 13, 2026

  • The Scope of Things: Tackling the Problematic Trio with Joseph Kim

    Clinical Research News | Clinical trials have always struggled with the problematic trio: study execution, patient recruitment, and engagement. In the newest episode of The Scope of Things, Joseph Kim, chief strategy officer of ProofPilot, spoke about the reason why these problems have still not been solved, despite repeated attempts.

    Feb 12, 2026

  • EverythingALS Advances a New Clinical Research Model for ALS Trials

    Clinical Research News | Clinical research in amyotrophic lateral sclerosis has long been hindered by subjective endpoints, slow enrollment, and limited tools for tracking disease progression. EverythingALS, a nonprofit initiative, is addressing those barriers with a speech-based digital biomarker designed to modernize how ALS trials are conducted and evaluated.

    Feb 11, 2026

  • AI’s Promise Hinges on Redesigning Workflows

    Clinical Research News | The promise of AI was on full display at last week’s SCOPE event in Orlando, peppering each of hundreds of presentations focused on the future of clinical research. Analysts have projected that AI in clinical trials will represent an $8 billion business segment by 2030, generating up to $110 billion per year in value to pharma, but that will not happen unless the workflows are redesigned.

    Feb 10, 2026