• Novel Blood Test Offers Early Cancer Treatment Response Monitoring in Clinical Trials

    Clinical Research News | A fragmentation-based blood test is providing pharmaceutical companies with a new way to monitor cancer treatment response in clinical trials, informing how drug efficacy is evaluated in early-stage development. Delfi Diagnostics has developed DELFI-TF (DELFI-tumor fraction), a research-grade assay that uses a unique fragmentation approach to detect circulating tumor DNA in blood samples.

    Jul 15, 2025

  • Smarter Starts, Stronger Trials: How Data is Driving Faster Site Activation

    Clinical Research News | Feasibility, site selection, and study startup remain some of the most time-consuming and unpredictable phases of drug development. They are also tightly interconnected, making even small delays or inefficiencies during this period especially impactful, rippling across a study’s timeline and budget and affecting site relationships and patient access.

    Jul 11, 2025

  • Scope of Things: Pragmatic Trials’ Growing Importance

    Clinical Research News | The growing importance of pragmatic clinical trials in healthcare research cannot be overstated. In the most recent episode of the Scope of Things podcast, host Deborah Borfitz speaks with Bethany Kwan, University of Colorado Anschutz Medical Campus, and Heather Smyth, Colorado School of Public Health. Together they explore the fundamental distinctions between traditional clinical trials and pragmatic research approaches, uncovering why this methodology is experiencing such significant growth in modern healthcare research.

    Jul 9, 2025

  • ICH E6(R3) Guidance: Elevating Trials through Collaboration

    Clinical Research News | After 15 years of development, Stanford University's Tom Soh is preparing to take his biosensor technology from laboratory rats to human volunteers. The device, which can continuously monitor molecules in flowing blood for up to seven days, represents a potential paradigm shift in clinical medicine.

    Jul 3, 2025

  • Stanford's Blood Flow Biosensor Heads to Human Trials

    Clinical Research News | After 15 years of development, Stanford University's Tom Soh is preparing to take his biosensor technology from laboratory rats to human volunteers. The device, which can continuously monitor molecules in flowing blood for up to seven days, represents a potential paradigm shift in clinical medicine.

    Jul 2, 2025

  • Walgreens ‘Built the Vessel’ for Making Clinical Trials a Care Option

    Clinical Research News | In the span of three years, Walgreens—an integral part of communities across the U.S. for well over a century—has positioned itself as a key player in the clinical trial ecosystem highlighted by more than 35 biopharma partnerships and the engagement of over 17 million customers participating in industry-sponsored studies. The thesis that co-locating trials where patients are “actually works."

    Jul 1, 2025

  • Follow the Money: Migraine Therapy, Reducing Trial Failure, More

    Clinical Research News | Salvia plans to further develop MySalvia Therapy in a multi-center, double-blind, sham-controlled study for people with chronic migraine; Vivodyne plans to scale its robotics+AI approach to testing on thousands of lab-grown, fully-functional human tissues, which aim to reduce human clinical trial failure; and more.

    Jun 25, 2025

  • Veeva, Sarah Cannon Research Institute Collaboration, City of Hope Receives Grant, More

    Clinical Research News | Veeva and Sarah Cannon Research Institute has entered a strategic collaboration; City of Hope was awarded an up to $23.7 million contract from the Advanced Research Projects Agency for Health within the US Department of Health and Human Services; and more.

    Jun 24, 2025

  • Beyond Vitals: How Patient-Generated Data is Driving AI’s Healthcare Transformation

    Clinical Research News | In recent years, AI in healthcare has attracted growing interest and investment, with new roles like Chief AI Officer and AI-specific policies underscoring its transformative potential. However, one critical factor is often overlooked: the quality of the data used to train AI algorithms. While AI’s impact is undeniable, its effectiveness depends on the depth, diversity, and granularity of the data it processes.

    Jun 20, 2025

  • Genetic Testing Transforms Medication Prescribing for Better Patient Outcomes

    Clinical Research News | The UK National Health Service’s PROGRESS trial has achieved remarkable clinical success, with one in four patients having their prescriptions adjusted based on genetic test results, leading to safer and more effective treatments. The PROGRESS trial’s interim results reveal that 95% of the 500 patients tested carried genetic variants that directly influence how they metabolize common medications.

    Jun 18, 2025

  • AI Agent Speeds Up Trials with Instant, Personalized Participant Interactions

    Clinical Research News | An artificial intelligence (AI) agent known as Grace is bringing clinical trials some much-needed speed and cost reduction and delivering more personalized, on-demand digital experiences for participants. Developed by fast-growing Grove AI, Grace has over the past year powered more than 50 phase 2 and 3 trials involving over 500,000 interactions with would-be and enrolled trial participants.

    Jun 17, 2025

  • IQVIA, NVIDIA Build AI Agents for Clinical Research

    Clinical Research News | Today, IQVIA announced multiple AI orchestrator agents in collaboration with NVIDIA. These specialized agentic systems—covering trial start-up, target identification, clinical data review, and more—are designed to manage and accelerate drug development workflows for IQVIA customers.

    Jun 11, 2025

  • Clinical Research Reveals Third Castleman Disease Subtype After 45 Years

    Clinical Research News | Researchers have made a landmark discovery in rare disease clinical research by identifying a new subtype of Castleman disease, marking the first major advancement in disease classification since the 1970s. The breakthrough demonstrates how patient-driven research registries can overcome traditional barriers in rare disease studies to generate clinically meaningful insights.

    Jun 10, 2025

  • Bridging the Gap Between GI Research and Routine Practice

    Clinical Research News | Gastroenterology is seeing meaningful progress in clinical research. New therapies for inflammatory bowel disease, colorectal cancer, and metabolic dysfunction-associated steatohepatitis (MASH) are being developed with increasing speed and precision. Yet for many community-based practices, participating in that research remains a significant challenge.

    Jun 6, 2025

  • Smart Bandage Technology Advances from Animal Models to Human Clinical Testing

    Clinical Research News | California Institute of Technology researchers have successfully transitioned their innovative "smart bandage" technology from preclinical animal studies to human clinical testing, marking a significant milestone in the development of real-time wound monitoring systems for chronic wound management.

    Jun 4, 2025

  • Many Approaches Collectively Aim at a Cure for Myeloma

    Clinical Research News | A small not-for-profit organization has set itself up as a model for turning the nitty-gritty of scientific research into a metaphorical “black swan event” with major impact on the lives of patients living with an incurable disease. The overarching strategy of the International Myeloma Foundation (IMF) is to function as the convener of the broader myeloma community in ways that lead to improved outcomes for patients in terms of both their quality and quantity of life.

    Jun 3, 2025

  • Follow the Money: PhaseV’s AI for Holistic Solutions, Carta’s AI Platform Transforms Clinical Data, More

    Clinical Research News | PhaseV intends to grow its vertical AI platform to provide holistic solutions for clinical development; Carta Healthcare is expanding to meet the surging demands among health systems and life sciences organizations for AI-driven innovation that can transform clinical data into valuable insights; and more.

    May 30, 2025

  • Weill Cornell, Regeneron’s New AI, Elsevier Adds Half a Million Records, More

    Clinical Research News | Weill Cornell Medicine and Regeneron Pharmaceuticals collaborated to develop a new AI-based method accurately sorts cancer patients into groups that have similar characteristics before treatment and similar outcomes after treatment; Elsevier announced the addition of half a million records from ClinicalTrials.gov to its leading biomedical literature database, Embase; and more.

    May 29, 2025

  • SCOPE 2025 Names West Clinical Research, Stitch as Site Innovation Award Winners

    Clinical Research News | West Clinical Research (WCR) and Stitch were named the Site Innovation Award winners at this year’s SCOPE Summit in Orlando. The Site Innovation Award at SCOPE recognizes sites and partnerships pioneering new approaches to improve clinical trials. WCR and Stitch’s collaboration produced a platform, also called Stitch, that is designed to optimize trial participants’ experiences while also improving other aspects of trial participation and for site staff labor.

    May 23, 2025

  • Multi-Center Study Validates AI Tools for Precision Cancer Diagnostics

    Clinical Research News | A clinical research initiative has demonstrated that artificial intelligence could significantly enhance the identification of patients eligible for targeted breast cancer therapies, according to preliminary findings presented by Friends of Cancer Research.

    May 21, 2025