• What Will It Take—And What Does It Look Like—For Clinical Care and Clinical Research To Converge?

    Clinical Research News | A profound shift is underway: one that positions patients not merely as recipients of clinical care but as active participants and collaborators in clinical research. A panel at last week’s SCOPE Summit Europe took on this challenge.

    Nov 4, 2024

  • SCOPE Europe 2024 Announces Best of Show Winners

    Clinical Research News | Clinical Research News and ClinEco announced three Best of Show winners today at the 2024 SCOPE Europe conference in Barcelona, Spain. The winning companies that submitted their products include Anju Software, Greenphire, and Medidata.

    Oct 30, 2024

  • IQVIA Introduces New AI Assistant, DHL Express, Thermo Fisher Partnership, Novel Cellular Blood Pressure Monitor, More

    Clinical Research News | IQVIA introduces IQVIA AI Assistant; DHL Express and Thermo Fisher Scientific join forces to drive more sustainable clinical research services; Withings Health Solutions announces a first-of-its-kind cellular blood pressure monitor; and more.

    Oct 30, 2024

  • Follow the Money: Trials for Major Depressive Disorder Therapies, Kidney Disease Treatment, More

    Clinical Research News | Seaport Therapeutics plans to advance their therapeutic candidate SPT-300, an oral prodrug of allopregnanolone; Purespring Therapeutics will initiate a clinical trial for IgAN, a common, chronic kidney disease primarily affecting young adults; and more.

    Oct 29, 2024

  • Advancing Health Equity: Community-First Approach to Drive Diversity in Clinical Research

    Clinical Research News | In clinical research, one ongoing challenge continues to persist: a lack of diverse representation. While the root cause stems from a combination of limited access and endemic mistrust of the health care system among certain communities, the outcome is that large pockets of communities are often excluded from studies, even in key areas where they are disproportionately affected by diseases such as diabetes, heart disease, and certain forms of cancer.

    Oct 25, 2024

  • SCOPE Europe 2024 Best of Show Entries

    Clinical Research News | The results are in: there are twelve new product finalists in the 2024 SCOPE Europe Best of Show awards that will be on display next week in Barcelona. Starting at the opening reception, the SCOPE Europe community is invited to identify exceptional innovation in technologies used by life science professionals, voting on the most impactful new products of the year.

    Oct 24, 2024

  • Drug Developers Eying Rollout of AI Legislation in the EU

    Clinical Research News | Eyes around the globe are on the EU Artificial Intelligence (AI) Act—the first comprehensive legal framework on AI anywhere—which will likely influence the direction of regulatory oversight measures adopted elsewhere, include other major markets such as the United States. Differing perspectives on the Act, including if and to what extent it could be a “death knell” for innovation, will be aired during a panel discussion being staged at the upcoming Summit for Clinical Ops Executives (SCOPE) Europe in Barcelona, Spain.

    Oct 22, 2024

  • Estrogen’s Impact on Cancer Reveals New Treatment Options

    Clinical Research News | A groundbreaking new approach for treating triple-negative breast cancer is moving forward, thanks to discoveries from Dr. Donald McDonnell’s lab at Duke University. Traditionally, hormone therapies have only been considered effective for estrogen receptor-positive cancers, but McDonnell’s research suggests that estrogen modulation could also impact TNBC.

    Oct 17, 2024

  • Psst! Need a Simple and Reliable Eye Tracker for Your Brain Studies?

    Clinical Research News | A mechanical engineer at the University of Houston is seeking physician collaborators with a research need for a small but sensitive wearable eye-tracking system to provide continuous data on human brain activity. The need was suggested by a survey of the literature, which found that a shortage of data coming from devices used in supervised clinical settings was resulting in inconclusive correlations study after study.

    Oct 15, 2024

  • Catching Up With Jill Pellegrino, Now Leading AutoCruitment

    Clinical Research News | For as long as most people can remember, patient enrollment into clinical trials has been abysmal—so much so that 80% of studies don’t finish on time and 55% end due to low accrual rates. The underlying issue is overreliance on study sites to find participants on their own.

    Oct 10, 2024

  • CluePoints Launches Medical & Safety Review (MSR) Software

    Clinical Research News | CluePoints has launched its Medical & Safety Review (MSR) tool that aims to simplify and streamline the medical analysis of study data through user-friendly dashboards, data manipulation and cleaning, query management and full transparency over the data history.

    Oct 9, 2024

  • Curing Data Collection Woes Could Take a Village

    Clinical Research News | The average clinical trial generates three times as much data as it did a decade ago, and yet there are no standards in place for how that information should be collected. That’s a big problem for many reasons, not the least of which is that drug developers may be missing key insights about the way interventions are working in individuals and across populations.

    Oct 8, 2024

  • Study Aims to Resolve Variants of Uncertain Significance

    Clinical Research News | A pioneering study led by Dr. Lachlan Jolly at the University of Adelaide’s Neurobiology Research Group is transforming genetic diagnostics by resolving variants of uncertain significance (VUS) using skin samples. Many patients with VUS lack a definitive diagnosis because RNA from disease-causing genes often can't be extracted from accessible tissues like blood or skin.

    Oct 3, 2024

  • Scope of Things: Trial Planning Skews Conclusions, AI Diversity Help, News of the Month

    Clinical Research News | In this month’s episode of the Scope of Things, host Deborah Borfitz covers everything you need to know about a pending launch of a large treatment trial for Graves’ disease, a recruitment campaign for a diagnostic tampon, Walgreens and BARDA’s new partnership, how eligibility criteria has been excluding people of African or Middle Eastern descent from cancer studies, and more.

    Oct 2, 2024

  • Follow the Money: GPCR Targets, Upacicalcet, AAV-Delivered Cancer Immunotherapy, More

    Clinical Research News | Superluminal Medicines is focusing on supporting the progression of their lead program into clinical development and increase the number of small molecule drug discovery programs focused on high-value G protein-coupled receptor (GPCR) targets; Pathalys Pharma wraps up upacicalcet clinical trials; Vironexis anticipates initiating patient enrollment of a Phase 1/2 trial of VNX-101 in the fourth quarter of 2024, which will mark the first-ever clinical trial of an AAV-delivered cancer immunotherapy; and more.

    Sep 26, 2024

  • AstraZeneca, Moffitt Cancer Center Partner, Firefly Neuroscience Advances AI Tech, More

    Clinical Research News | Moffitt Cancer Center announced a strategic collaboration with AstraZeneca that aims to accelerate the development of cell therapies, specifically chimeric antigen receptor T cell and T cell receptor therapies; Firefly Neuroscience announced the advancement of its artificial intelligence-powered Brain Network Analytics (BNA) technology; and more.

    Sep 25, 2024

  • PCORI Offers $100 Million For Youth Research, Children’s Health Promotion

    Clinical Research News | PCORI announced earlier this month that they are inviting proposals through eight new funding opportunities. These include three PCORI Funding Announcements for patient-centered comparative clinical effectiveness research (CER). Letters of intent are due October 1, 2024, and applications will be accepted until January 14, 2025.

    Sep 24, 2024

  • Flatiron Health Expands its Mission to Make Trials More ‘Pragmatic’

    Clinical Research News | The patient groups more likely to be treated at community practices with limited or no access to oncology clinical trials are the same groups historically underrepresented in such trials, finds a nationwide study conducted by Flatiron Health. The reasons for this are unknown, but the research effectively rules out quality of care and location of the practices.

    Sep 19, 2024

  • Trial Emulation Study Taps Real-World Data to Help Fill Evidence Gaps

    Clinical Research News | Researchers in the UK recently emulated a large, randomized controlled trial (RCT) testing the effectiveness of two blood thinners using data from real-world patients to help understand whether the real-world data can be used to explore treatment effects in people underrepresented in the study. While results of the reference trial and its simulation didn’t entirely align, the approach could help fill the evidence gap for population groups largely missing in RCTs.

    Sep 17, 2024

  • New Treatment Option for Graves’ Disease Finally ‘On the Horizon’

    Clinical Research News | Later this year, Immunovant will be launching a late-stage clinical trial for Graves’ disease—the first in a very, very long time. The preferred treatment option currently is methimazole, approved for medical use in the U.S. in 1950, but some patients require high doses of the drug to control their hyperthyroidism, and in up to half of cases long-term remission isn’t achievable short of surgery to remove the thyroid gland or radioactive iodine to destroy the thyroid and stop it from producing hormones.

    Sep 12, 2024