• Novel Mouse Avatars Could Advance Personalized Medicine For Cancer

    Clinical Research News | Up to now, mouse avatars haven’t proven to be particularly good tools for forecasting treatment response in human cancer patients. But new models being generated by an international team of researchers are expected to be far more predictive of what is going to happen with different cohorts of clinical trial participants.

    May 3, 2023

  • Ardy Arianpour on Seqster’s Mission, Growth, and Pharma Tipping Point

    Clinical Research News | When Seqster was first founded in 2016, co-founder Ardy Arianpour had a lot of experience in next-gen sequencing and a vision for how consumers could control their health information. Seqster is more than a company, Arianpour insists to host, Deborah Borfitz, in the latest Scope of Things podcast. “This is a movement.”

    May 2, 2023

  • Patient Platform from Greenphire, Medidata AI Platform, More

    Clinical Research News | Greenphire launches a new patient-facing digital platform, Medidata’s AI Intelligent Trials platform will support Launch Therapeutics, gold-based compounds target “superbugs”, The University of Chicago Medicine Comprehensive Cancer Center has been named the newest member institution of the National Comprehensive Cancer Network Agency, and more.

    Apr 27, 2023

  • PEACE Study Offers New Clues About How Cancer Resists Treatment

    Clinical Research News | Research autopsies are nothing new—the use of post-mortem tissues for cancer research has been ongoing since the end of the nineteenth century—but the Cancer Research UK-sponsored PEACE (posthumous evaluation of advanced cancer environment) study stands apart by virtue of its scope and scale. The pan-cancer initiative intends to enroll 500 patients across the country in hopes of understanding cancer evolution, drug resistance and why patients die of their disease.

    Apr 26, 2023

  • Follow the Money: PCORI Funding, Bipolar Disorder Investments, Decentralized Trial Funding, More

    Clinical Research News | PCORI has announced $127M in investment for research projects targeting high-burden healthcare concerns; Gilde Healthcare announces a new fund for medtech; Series C for a FHIR-native health data platform; and more.

    Apr 25, 2023

  • Army Researchers Identify Blood Biomarker Panel For PTSD

    Clinical Research News | Post-traumatic stress disorder is difficult to diagnose under the best of conditions, including knowing the triggering issues and how an individual responds to stressful events. For the mostly young and “macho” men in the military who are exposed to combat and separated from their families for many months at a stretch the obstacles—and stakes—are even higher.

    Apr 20, 2023

  • AI-Based Retinal Aging Clock Gauges Effectiveness Of Anti-Aging Interventions

    Clinical Research News | Retinal scans offer a fascinating window into the health of the body’s circulatory system and brain functioning as well as identify eye diseases that aren't visibly noticeable. Now, a new study suggests that this artificial intelligence-based technology is also good for predicting how well people are aging.

    Apr 18, 2023

  • Three Ways AI Can Accelerate Innovations in Clinical Research

    Clinical Research News | Artificial Intelligence (AI-) powered software is demonstrating great potential to accelerate and improve participant screening and enrolment in clinical trials. It is also enhancing communication and collaboration between clinical research teams. These elements combined are resulting in improved productivity and better ROI for clinical trials.

    Apr 14, 2023

  • Global Collaboration Enables Headway On Rare Neuroendocrine Tumors

    Clinical Research News | Researchers in Madrid recently wrapped up the largest-yet genomic study of rare neuroendocrine tumors, known as pheochromocytomas and paragangliomas, which identified a seemingly perfect panel of metastatic disease markers as well as a group of patients who could potentially benefit from immunotherapy. The objective here is a better means to predict, at the time of diagnosis of the primary tumor, whether patients will be immediately affected by cancer spread.

    Apr 12, 2023

  • Multi-Purpose Cancer Drug Could Extend Life Of Terminally Ill Cancer Patients

    Clinical Research News | A small company based in Norway is taking on the global-sized challenge of cancer treatment, notably including solid tumors and hematological malignancies. The means is a promising, highly specific drug, known as ATX-101, whose molecular target orchestrates many different processes in the cells.

    Apr 11, 2023

  • Liquid Biopsies Could Help Speed Up Lung Cancer Clinical Trials

    Clinical Research News | Circulating tumor DNA (ctDNA) holds potential as a biomarker in lung cancer clinical trials as an added and easier-to-monitor endpoint to survival rates for measuring treatment efficacy. This was one of the key findings of her most recent work, where ctDNA was also shown to outperform clinical responses assessed on CT scans in the prediction of survival.

    Apr 6, 2023

  • Dr. Su Golder on Reporting Adverse Events in Clinical Research

    Clinical Research News | Su Golder, associate professor and senior research fellow in the Department of Health Sciences at the University of York, speaks with the Scope of Things podcast host Deborah Borfitz about adverse event reporting and the challenges that hinder its consistent practice in the health sciences community.

    Apr 4, 2023

  • USC Addresses Brain Research Diversity Crisis in India, Pfizer Advances Research for Additional COVID-19 Treatments, More

    Clinical Research News | A clinical trial supply forecasting service helps inform decision-making related to the quantity of medication produced for use in clinical development; a new innate immune biology lab to study the innate immune system and its cells; a post-stroke atrial fibrillation (AF) platform collects real-time imaging data and securely transfers it to the central investigators to improve the detection of AF; and more.

    Mar 30, 2023

  • Dealing With Data Biases and Overwhelm in Clinical Research

    Clinical Research News | At a panel presentation during the ViVE event in Nashville, Tenn., on Monday, Kulleni Gebreyes of Deloitte, hosted a discussion about unbiased data in health care.

    Mar 29, 2023

  • Follow the Money: University of Utah Accelerates Heart Failure Gene Therapy Research, OpenClinica’s Cloud Technology to Simplify Clinical Trials, More

    Clinical Research News | Funding for progressing a neurodegenerative disease drug candidate into clinical development, virus filters engineered to provide superior filter productivity and robust viral clearance during clinical trials, developing messenger RNA therapies for applications in cancer immunotherapy and exploring therapeutic alternatives with various nucleic acids, and more.

    Mar 28, 2023

  • MUSC’s Opt-Out Approach To Recruitment Proves Popular With Patients

    Clinical Research News | Consumers are by now accustomed to opting out of everything from unwanted telemarketing calls to text messages about a flash sale at their favorite department store. It is perhaps unsurprising then that they would not object to the idea of an opt-out approach to cold contact about a clinical trial for which they are potentially eligible.

    Mar 23, 2023

  • Gender Parity Still A Stretch Goal For Global Trials

    Clinical Research News | Two different perspectives on the participation of women in clinical trials arise when looking at the situation locally and internationally. At the ground level in the U.S., at least on protocols that don’t exclude them, women often outnumber men by a wide margin even if all socioeconomic subgroups aren’t represented. On the other hand, females account for only about 31% of study participants across all 450,000 ongoing global trials.

    Mar 15, 2023

  • Community Pharmacists Can Help Sponsors Meet Trial Diversity Requirements

    Clinical Research News | Independent, community-based pharmacists are in an ideal position to improve the equitable representation of racial and ethnic groups in clinical research, as required under the recently enacted 2023 omnibus spending bill. How to accomplish this is spelled out in a white paper, termed the Diversity Now protocol, newly published by the company that focuses on improving the recruitment and retention of underrepresented populations.

    Mar 14, 2023

  • ‘Circle Of Trust’ Model For Recruiting Indigenous Populations Into Trials

    Clinical Research News | An existing trust-based intervention known to increase minority participation in clinical trials won’t do much to improve the representation of American Indians (AI) and Alaska Natives (AN) in studies, according to Arch G. Mainous III, Ph.D., professor in the department of community health and family medicine as well as health services research, management and policy at the University of Florida. Community engagement is critical when dealing with indigenous populations from a particular tribe or reservation.

    Mar 9, 2023

  • Jill Pellegrino of CVS Health Clinical Trial Services on Using RWE to Improve Clinical Trial Efficiency and Applicability

    Clinical Research News | In 2020, retail pharmacy giant CVS launched CVS Health Clinical Trial Services to increase patient recruitment efforts and encourage equitable participation. In the latest Scope of Things podcast episode, Jill Pellegrino, vice president of recruitment and RWE at CVS Health Clinical Trial Services, speaks with host Deborah Borfitz about the company’s extensive clinical trial offerings.

    Mar 7, 2023