• Realizing The Benefits Of Bringing The Trial To The Patient

    Clinical Research News | During the worst days of the COVID-19 pandemic, drug sponsors, clinical sites, and patients alike discovered the value of in-home services in allowing research studies to proceed while minimizing patients’ potential exposure to the virus from on-site visits. Such services were a lifeline to the research industry. Today, in-home services are being baked into trial protocols not out of dire necessity, but rather out of an appreciation for their value in supporting patient-centric trials with decentralised components.

    May 26, 2023

  • News and Products from Trialbee, Flatiron, Sanofi, Phesi, Personalis, More

    Clinical Research News | Trialbee enhances recruitment strategy; Flatiron and Sanofi set out to redesign the clinical trial experience for sponsors, sites, and patients; and Phesi has published the first edition of its Digital Patient Profile (DPP) catalog. Plus: partnerships for Culmination Bio, Cofactor Genomics, Personalis, Ono Pharmaceuticals, National Cancer Center, and more.

    May 24, 2023

  • As CVS Slowly Exits Clinical Trial Business, Walgreens Continues Ramp-Up

    Clinical Research News | Last week, CVS Health announced its intension to phase out of the clinical trial business with a full exit expected by the end of 2024. In a conversation with Clinical Research News, Walgreens Chief Clinical Trials Officer Ramita Tandon applauds her colleagues at CVS for being the first mover. She is also reassuring Walgreens stakeholders that “we are not going away.”

    May 23, 2023

  • New Antimicrobial Susceptibility Test Suggests Generic Z-Pak Can Cure Superbugs

    Clinical Research News | A new antimicrobial susceptibility testing (AST) method developed by scientists at the University of California, Santa Barbara, resolves the longstanding conflict between what the gold-standard assay says will work and actual patient outcomes when it comes to selecting antibiotics. The alternative AST protocol reveals that antibiotics already widely available on the market can cure superbugs.

    May 18, 2023

  • Blinded, Randomized Clinical Trial Suggests AI ‘Near-Ready For Prime Time’

    Clinical Research News | In a first-of-its-kind, blinded and randomized clinical trial of artificial intelligence (AI) in cardiology, investigators at Cedars-Sinai Medical Center have shown that an “AI assistant” for assessing heart health works even better than sonographers at reading echocardiograms. The software was integrated with the institution’s picture archiving and communication system that securely stores and digitally transmits electronic images.

    May 16, 2023

  • Data Matters: Creating the Perfect Health Research Cohort

    Clinical Research News | Research scientists know that an important foundation of research is cohort creation; many critical decisions are made based on how the cohort is built and designed. Better cohort creation can lead to more accurate findings and better care outcomes. But how do you build a better cohort? It all starts with the research question and the data at hand.

    May 12, 2023

  • Parkinson’s Disease Trials Need Better Markers Of Cognitive Changes

    Clinical Research News | The instruments commonly used to assess cognitive decline in Parkinson’s disease (PD) patients enrolled in neuroprotective clinical trials are “poorly suited to the task,” according to industry consultant Travis Turner, Ph.D., assistant professor and director of the neuropsychology division at Medical University of South Carolina, and senior clinical director for movement disorders at WCG. “I strongly suspect that good interventions have been discarded because [of] the tests that were trying to measure efficacy.”

    May 10, 2023

  • Predictive Analytics Giving The Lowdown on Clinical Trial Performance

    Clinical Research News | A data-agnostic integration platform for optimizing trial planning and conduct hit the streets three years ago, bringing near-real-time insights about every participant, site, country, region, and study to companies struggling to reduce the cost and speed the pace of clinical research. The technology, powered by machine learning, is currently underpinned by data from more than 2,000 trials and over 400,000 healthcare providers.

    May 9, 2023

  • Novel Mouse Avatars Could Advance Personalized Medicine For Cancer

    Clinical Research News | Up to now, mouse avatars haven’t proven to be particularly good tools for forecasting treatment response in human cancer patients. But new models being generated by an international team of researchers are expected to be far more predictive of what is going to happen with different cohorts of clinical trial participants.

    May 3, 2023

  • Ardy Arianpour on Seqster’s Mission, Growth, and Pharma Tipping Point

    Clinical Research News | When Seqster was first founded in 2016, co-founder Ardy Arianpour had a lot of experience in next-gen sequencing and a vision for how consumers could control their health information. Seqster is more than a company, Arianpour insists to host, Deborah Borfitz, in the latest Scope of Things podcast. “This is a movement.”

    May 2, 2023

  • Patient Platform from Greenphire, Medidata AI Platform, More

    Clinical Research News | Greenphire launches a new patient-facing digital platform, Medidata’s AI Intelligent Trials platform will support Launch Therapeutics, gold-based compounds target “superbugs”, The University of Chicago Medicine Comprehensive Cancer Center has been named the newest member institution of the National Comprehensive Cancer Network Agency, and more.

    Apr 27, 2023

  • PEACE Study Offers New Clues About How Cancer Resists Treatment

    Clinical Research News | Research autopsies are nothing new—the use of post-mortem tissues for cancer research has been ongoing since the end of the nineteenth century—but the Cancer Research UK-sponsored PEACE (posthumous evaluation of advanced cancer environment) study stands apart by virtue of its scope and scale. The pan-cancer initiative intends to enroll 500 patients across the country in hopes of understanding cancer evolution, drug resistance and why patients die of their disease.

    Apr 26, 2023

  • Follow the Money: PCORI Funding, Bipolar Disorder Investments, Decentralized Trial Funding, More

    Clinical Research News | PCORI has announced $127M in investment for research projects targeting high-burden healthcare concerns; Gilde Healthcare announces a new fund for medtech; Series C for a FHIR-native health data platform; and more.

    Apr 25, 2023

  • Army Researchers Identify Blood Biomarker Panel For PTSD

    Clinical Research News | Post-traumatic stress disorder is difficult to diagnose under the best of conditions, including knowing the triggering issues and how an individual responds to stressful events. For the mostly young and “macho” men in the military who are exposed to combat and separated from their families for many months at a stretch the obstacles—and stakes—are even higher.

    Apr 20, 2023

  • AI-Based Retinal Aging Clock Gauges Effectiveness Of Anti-Aging Interventions

    Clinical Research News | Retinal scans offer a fascinating window into the health of the body’s circulatory system and brain functioning as well as identify eye diseases that aren't visibly noticeable. Now, a new study suggests that this artificial intelligence-based technology is also good for predicting how well people are aging.

    Apr 18, 2023

  • Three Ways AI Can Accelerate Innovations in Clinical Research

    Clinical Research News | Artificial Intelligence (AI-) powered software is demonstrating great potential to accelerate and improve participant screening and enrolment in clinical trials. It is also enhancing communication and collaboration between clinical research teams. These elements combined are resulting in improved productivity and better ROI for clinical trials.

    Apr 14, 2023

  • Global Collaboration Enables Headway On Rare Neuroendocrine Tumors

    Clinical Research News | Researchers in Madrid recently wrapped up the largest-yet genomic study of rare neuroendocrine tumors, known as pheochromocytomas and paragangliomas, which identified a seemingly perfect panel of metastatic disease markers as well as a group of patients who could potentially benefit from immunotherapy. The objective here is a better means to predict, at the time of diagnosis of the primary tumor, whether patients will be immediately affected by cancer spread.

    Apr 12, 2023

  • Multi-Purpose Cancer Drug Could Extend Life Of Terminally Ill Cancer Patients

    Clinical Research News | A small company based in Norway is taking on the global-sized challenge of cancer treatment, notably including solid tumors and hematological malignancies. The means is a promising, highly specific drug, known as ATX-101, whose molecular target orchestrates many different processes in the cells.

    Apr 11, 2023

  • Liquid Biopsies Could Help Speed Up Lung Cancer Clinical Trials

    Clinical Research News | Circulating tumor DNA (ctDNA) holds potential as a biomarker in lung cancer clinical trials as an added and easier-to-monitor endpoint to survival rates for measuring treatment efficacy. This was one of the key findings of her most recent work, where ctDNA was also shown to outperform clinical responses assessed on CT scans in the prediction of survival.

    Apr 6, 2023

  • Dr. Su Golder on Reporting Adverse Events in Clinical Research

    Clinical Research News | Su Golder, associate professor and senior research fellow in the Department of Health Sciences at the University of York, speaks with the Scope of Things podcast host Deborah Borfitz about adverse event reporting and the challenges that hinder its consistent practice in the health sciences community.

    Apr 4, 2023