• SCOPE Preview: Patient-Centricity, Real-World Evidence, and the Evolution of Clinical Trial Design

    Clinical Research News | Clinical Research News will be attending the Summit for Clinical Ops Executives—SCOPE—in Orlando, Fla. from February 6-9, 2023. Here are just a few of the items from the agenda we’ve flagged so far.

    Jan 10, 2023

  • Trendspotting: Hybrid and Decentralized Clinical Trials, Patient-Centricity, and Increased Remote Patient Monitoring in 2023

    Clinical Research News | We spoke with clinical research leaders about their expectations for the coming year. They predicted that hybrid and decentralized trials (DCTs) would eventually become the industry standard, brick-and-mortar sites will employ flexibility to increase patient retention, and companies will rely heavily on remote patient monitoring and wearable devices to stretch their budgets and combat the looming economic downturn.

    Jan 5, 2023

  • AbbVie’s Christopher Boone on Disrupting the Clinical Research Enterprise With Real-World Data and Evidence

    Clinical Research News | In recent years, pharmaceutical and life science companies have leveraged real-world evidence (RWE) to maximize patient recruitment and formulate clinical trial criteria. In the latest episode of the Scope of Things podcast, Christopher Boone, Ph.D., vice president and global head of health economics and outcomes research at AbbVie, talks about the disruptive nature of RWE and its impact on clinical trial design.

    Jan 3, 2023

  • Top Stories of 2022: Decentralized Trials, Data Science for Trials

    Clinical Research News | Decentralized trials have been on everyone’s lips this past year. The first real data coming in on the success and value of new trial formats has also prompted other questions around standardizing vocabulary, prioritizing the incorporation of new pharmacists, and more. In addition, new data science technologies including machine learning and “tokenization” aim to shape clinical research.

    Dec 29, 2022

  • IllumiCare App Recommends Trials as Therapeutic Option, New Data Capture Interface Increases Real-World Patient Compliance, More

    Clinical Research News | A 16-gene molecular signature investigation based on gene expression differences between patients with and without local recurrence after breast-conserving surgery; analytically sensitive infectious disease panels to support laboratory research; eClinical solutions to make clinical research processes more efficient and compliant; and more.

    Dec 27, 2022

  • Follow the Money: MD Anderson’s High-Affinity Monoclonal Antibody Research, New Neurodegeneration Research Center, More

    Clinical Research News | Funding for microbial resistance and infectious disease research, tracking Long COVID in diverse pediatric and adult populations, an AI-powered platform that identifies novel cancer therapies and predicts the efficacy of cancer drug combinations, and more.

    Dec 22, 2022

  • ClinEco Helps Trial Stakeholders ‘Cut Through The Noise’ To Find One Another

    Clinical Research News | The world’s first B2B market network for clinical trials is now fully functioning and onboarding, as well as learning, from early adopters. ClinEco recently moved into the open beta stage of its development with a gratifyingly diverse mix of stakeholders registering for free membership.

    Dec 20, 2022

  • Insilico Medicine’s AI-Driven Platform Pushes The Envelope Of Drug Discovery

    Clinical Research News | During a recent virtual unveiling party livestreamed from around the world, Insilico Medicine introduced the latest updates to Pharma.AI, its end-to-end drug discovery platform using generative artificial intelligence to discover new targets, design new molecules, and predict the outcome of clinical trials. Among the highlights were the addition of a knowledge graph to target discovery product PandaOmics and numerous new panels to generative chemistry engine Chemistry42.

    Dec 15, 2022

  • In Virtual Trials, Two Alzheimer’s Drugs Do Poor Job Of Slowing Cognitive Decline

    Clinical Research News | Researchers from Duke, Penn State, and the University of Tennessee collaboratively built a mathematical model of Alzheimer’s disease that used real, de-identified patient data to simulate health outcomes from a pair of anti-amyloid-beta drugs. Notably, the virtual (aka in silico) clinical trials employed a computational approach that provides “individualized prescriptions” based on optimal timing and dosing of treatment while minimizing possible side effects.

    Dec 14, 2022

  • Killing Cancer With Synthetic Lethality

    Clinical Research News | A key member of the team that discovered the BRCA2 breast cancer susceptibility gene in 1995 is now enamored of the idea of taking on cancer with synthetic lethal therapies, a nontraditional approach that exploits the weaknesses of cancer cells. The promise of the treatment concept was the topic of the Heath Memorial Award keynote address delivered at the recent Leading Edge of Cancer Research Symposium of the University of Texas MD Anderson Cancer Center.

    Dec 13, 2022

  • 2023 Participant Engagement Awards Finalists Named

    Clinical Research News | Finalists have been named for the 7th Annual Participant Engagement Award. Winners will be announced after a live presentation and judging session at the Summit for Clinical Ops Executives. This year’s SCOPE Summit will be held February 6-9, 2023, in Orlando, Fla.

    Dec 8, 2022

  • Dr. Loaiza-Bonilla on Massive Bio’s Efforts to Make Clinical Trials More Accessible for Cancer Patients

    Clinical Research News | In the latest episode of the Scope of Things podcast, host Deborah Borfitz speaks with Dr. Arturo Loaiza-Bonilla, co-founder and chief medical officer of Massive Bio, about increasing clinical trial access for cancer patients and offering next-generation enrollment services.

    Dec 6, 2022

  • Clinical Research News, ClinEco Launch SCOPE Best of Show Awards

    Clinical Research News | The Summit for Clinical Ops Executives has long been the most impactful destination for in-depth discussions in clinical research. Now the SCOPE community will wield its significant expertise to highlight the new products powering clinical research in the SCOPE Best of Show Awards brought to you by Clinical Research News and ClinEco, the global clinical trials ecosystem and marketplace.

    Dec 1, 2022

  • Super Agers Initiative Uncovers Biological Mysteries of Longevity, MD Anderson’s Novel Small-Molecule Oncology Therapies Research, More

    Clinical Research News | A newly developed immunotherapy drug that delays the onset of type 1 diabetes in at-risk individuals by an average of almost three years; a study to engineer a human heart model, elucidate fundamental laws of muscular pumps, and apply lessons learned to a cardiovascular bio digital twin model; a highly flexible, modular patent-pending platform and wearable sensor designed to meet the specific needs of clinical trials and remote patient research; and more.

    Nov 30, 2022

  • Follow the Money: Global Digital Therapeutics Clinical Research, Targeted and Minimally Invasive Anti-Cancer Research Platform, More

    Clinical Research News | Funding for clinical-stage urologic oncology pipeline, novel brain cancer research platform, immune microenvironment research of triple-negative breast cancer, and more.

    Nov 29, 2022

  • Pistoia Alliance Works to Mine RWD From Social Media

    Clinical Research News | The Pistoia Alliance has launched a new Community of Experts (CoE) to harness real-world data from social media. The CoE aims to develop best practices and guidelines to use social media analysis as real-world data for patient-focused drug development.

    Nov 22, 2022

  • Vivli To Expand Due To New Data-Sharing Policy Affecting NIH-Funded Research

    Clinical Research News | There is little doubt about the “data magnetism” of Vivli, an open-access, data-sharing platform integrating clinical trial data contributed by biopharmaceutical sponsors, academic institutions, and nonprofit foundations around the world. Vivli was created as a generalist repository in 2018 and since then has driven 126 new research findings—all publicly disclosed, primarily in the peer-reviewed literature.

    Nov 16, 2022

  • Social Determinants Of Health Data Help Identify Sites For Trials

    Clinical Research News | The movement toward decentralized clinical trials isn’t the only emerging trend that could help bump up clinical trial diversity. So, too, could the use of social determinants of health insights to better choose the sites and investigators most likely to enroll underrepresented individuals.

    Nov 15, 2022

  • Five Ways to Minimize Drug Development Costs

    Clinical Research News | The worldwide population is aging, and the prevalence of many diseases is on the rise, making rapid drug discovery and approval ever more critical. However, the cost of bringing a new drug to market is substantial. Using newer technologies, drug companies may be able to reduce costs associated with development and ultimately enhance their odds of successful approvals by improving the efficiency of clinical trials.

    Nov 11, 2022

  • Open-Source Platform Matches Cancer Patients to Precision Medicine Trials

    Clinical Research News | An open-source computer platform developed at Dana-Farber Cancer Institute is adding ease and speed to the process of matching cancer patients to trials of therapies targeting genomic alterations. The matching tool, which links individual clinical and genomic information to trial eligibility data in real time, is designed to help overcome the stubbornly low precision medicine trial participation rate despite more common use of genomic profiling.

    Nov 9, 2022