• The Scope of Things: Jasmine Smith and Dr. Deborah Duong on the First Decentralized AI Longevity Research Network

    Clinical Research News | With the latest innovations in medicine often prohibitively expensive, Rejuve.AI’s Jasmine Smith, CEO, and Dr. Deborah Duong, CTO, help patients achieve a healthy and extended lifespan regardless of economic standing. In the latest episode of the Scope of Things podcast, they, along with podcast host, Deborah Borfitz, discuss the world’s first decentralized AI longevity research network that provides equitable health and wellness solutions.

    Jun 7, 2022

  • Guardant and IQVIA Develop Precision Oncology Platform to Normalize Clinical Data

    Clinical Research News | Innovative Practices Award | Extracting high-quality data from clinical records can be time-consuming and costly, primarily when manual abstractors are tasked with mining complex, unstructured, and lengthy documents. That’s why the scientists at Guardant Health and Linguamatics, an IQVIA company, launched a real-world evidence database called GuardantINFORM. The platform was named one of the 2022 Bio-IT World Innovative Practices award winners.

    Jun 2, 2022

  • Chasing Digital Twins: Pilot Project Tackles Cancer Patient Twins in Neuro-Oncology

    Clinical Research News | At the Bio-IT World Conference & Expo last month, a team of researchers reported on their 12-week pilot effort to build cancer patient digital twins to aid in oncologist decision-making.

    Jun 1, 2022

  • World’s First Clinical Trials Ecosystem and Marketplace About To Open

    Clinical Research News | As the world’s first clinical trial ecosystem and marketplace, ClinEco—launching in beta this summer—is designed to connect study sponsors in need of clinical trial support with the full range of clinical trial technology and service providers.

    May 31, 2022

  • Unleashing the Value of Study Data with Digital Health Technology

    Clinical Research News |In recent years, a slew of digital health technologies (DHTs), designed to collect and share data remotely, have emerged to capture more data from clinical trials. And while uptake has been slow, new guidelines and regulations from the United States and European Union are finally creating a practical framework for an operation that promises to shift the dial. But do we finally have the structures we need to build 21st-century clinical trials that hasten access to life-saving treatments? Or is there more we could be doing with data?

    May 27, 2022

  • Cloud-Based Registry for HIV Clinical Study, Next-Gen Gene and Cell Therapy Research, More

    Clinical Research News | NIAID awards $577 million to establish nine Antiviral Drug Discovery Centers; Allelica and Invitae build clinical artificial intelligence architecture for breast cancer; a new COVID-19 antibody test is used in vital pandemic research; next-generation gene and cell therapy research promote more efficient clinical trials; and more.

    May 26, 2022

  • Follow the Money: Patient-Centric Clinical Trials, Cancer Research Biomarkers, More

    Clinical Research News| Funding for virtual and hybrid clinical trial and execution models, cancer research, pharmaceutical analytics, and more.

    May 25, 2022

  • Soft Skills Critical To Clinical Trial Continuity In Ukraine

    Clinical Research News | The importance of clinical trials as a care option in Ukraine, and the unthinkable bravery of its citizens since Russia launched the first bomb on Feb. 21, were predominant themes of a recent DIA webinar on the impact of the crisis on patients and clinical development.

    May 24, 2022

  • Patient Advocacy Groups Band Together To Further Rare Disease Research

    Clinical Research News | The fast-growing Consortium for Outcome Measures and Biomarkers for Neurodevelopmental Disorders (COMBINEDBrain) represents patient advocacy organizations for individuals with rare, neurodevelopmental diseases who are disadvantaged by the small number of affected individuals and scientific brainpower to lead the way.

    May 19, 2022

  • In War-Torn Ukraine, Clinical Trials Trudge Along

    Clinical Research News | The clinical research situation in Ukraine has changed from “peaceful, predictable, and promising” a year ago to “complex, complicated, and difficult” since the Feb. 24 Russian invasion, according to Serhiy Mykhaylov, Merck’s clinical research director in the country speaking during a recent DIA webinar on the ethical dilemmas the war has created for those supporting study participants in the region. As of six months ago, Ukraine had 500 active ongoing studies.

    May 17, 2022

  • Sequencing-Based Initiative Now Exploring How Best To Return The Findings

    Clinical Research News | A pioneering program of Geisinger Health System has returned clinically actionable results from exome sequencing to a record-breaking 3,400 individuals at increased risk for potentially life-threatening conditions such as hereditary breast and colon cancers, familial hypercholesterolemia (FH), and heart disease. The MyCode Community Health Initiative, enabled by a 2014 agreement with Regeneron Pharmaceuticals, draws from participants in a sizable DNA biobank who agree to the sequencing and results reporting.

    May 11, 2022

  • Liquid Biopsy Test Shows Promise For Pediatric Glioma

    Clinical Research News | Evidence is emerging that cerebrospinal fluid (CSF) testing might be useful in clinical settings for monitoring tumor growth and treatment response in pediatric patients with diffuse midline glioma (DMG), a lethal high-grade brain tumor that is inoperable and unlikely to be cured. Only about 500 new cases get diagnosed in the U.S. in any given year, but over two-thirds of them carry the exact same mutation (H3 K27M) allowing development of an assay that analyzes cell-free tumor DNA samples using digital droplet polymerase chain reaction (ddPCR).

    May 10, 2022

  • Future-Proofing Trials with HCP Selection to Improve Source Data and Quality Management for Sponsors and CROs

    Clinical Research News | Accurate information is the foundation of any quality research study, particularly when the study is decentralized or takes a hybrid approach. For decentralized clinical trials (DCTs), the appropriate selection of healthcare practitioners is all the more important to ensure patient care and data integrity.

    May 6, 2022

  • The Scope of Things: Ken Getz’s Data-Driven Approach to Patient Engagement

    Clinical Research News | Ken Getz and host Deborah Borfitz explore patient engagement for the newest episode of the Scope of Things podcast. Getz, Executive Director & Research Professor at the Tufts Center for the Study of Drug Development (CSDD), shares what his research has revealed about how patient engagement efforts are progressing, where we’re stuck in a rut, and a crucial misalignment in the industry’s view of patient engagement and what clinical research participants actually want.

    May 3, 2022

  • Follow the Money: Digital Twins in Clinical Research, Virtual Care and Digital Medicine, More

    Clinical Research News | Funding for digital twin use in clinical trials, immune-oncology cancer therapeutics, and virtual care and digital medicine, and more.

    Apr 29, 2022

  • AI and ML in Clinical Trials; Risk Management Software Update; Synthetic Control Arms; Decentralized Clinical Trials; More

    Clinical Research News | AI and ML in clinical trials, patent for minimum residual tumor detection, T-cell receptor engineering for cancer treatment, award given for COVID-19 clinical trial activities, synthetic control arms and decentralized trials, and more.

    Apr 28, 2022

  • Pragmatic Trial Suggests It May Take A Village To Tap Full Potential Of Genomics

    Clinical Research News | In a pragmatic clinical trial at a pair of health systems in New York City, researchers at the Mount Sinai Health System have determined that the full potential of genomics to improve clinical patient management may well depend on engaging community-based racial and ethnic minority groups in the effort. The National Institutes of Health is now funding a large, comprehensive nationwide study (GUARDD-US) through the Implementing Genomics in Practice (IGNITE) network aimed both at changing health behaviors and making pharmacogenomics-based treatment recommendations.

    Apr 25, 2022

  • Continuous Bioprocessing of Biologics: The Future is Bright

    Clinical Research News | While most medicines are derived from chemical compound, biologics are now the fastest-growing drug class. To deliver these complex drugs to patients as quickly as possible, the biopharmaceutical industry is shifting away from traditional batch processing to continuous bioprocessing.

    Apr 22, 2022

  • CLIA-Certified Alzheimer’s Blood Test Gets High Marks In Global Study

    Clinical Research News | A blood test to help clinicians diagnose Alzheimer’s disease is “on the road” to effectively replacing cerebrospinal fluid (CSF) testing and PET scans for detecting Alzheimer’s pathology, according to Randall J. Bateman, M.D., a professor of neurology at Washington University School of Medicine and co-developer of the plasma protein assay. A commercial version of the test, PrecivityAD, is already being used extensively in clinical trials as well to evaluate patients in real-world settings.

    Apr 19, 2022

  • ‘Professional Patient’ Detection Now A Clinical Study Essential

    Clinical Research News | After more than a decade in the business of detecting “professional patients,” Verified Clinical Trials is a familiar name to stakeholders across the research enterprise—including the nefarious players who ride-share from city to city in search of unprotected sites where they can enroll in studies purely for the financial gain. It’s an underappreciated underground economy that is costing sponsor companies time and money and, in some cases, completely shutting down studies, according to Mitchell Efros, M.D. FACS, CEO of Verified Clinical Trials.

    Apr 13, 2022