• Tackling the Logistical Challenges of DCTS: Joined Up Services and Owning the Process

    Clinical Research News | When hybrid and decentralized clinical trials rely on a patchwork of different suppliers, vendors, and couriers, logistics become a substantial administrative burden for sponsors and sites alike. That’s why an integrated project management approach to home health and distribution is vital.

    Mar 3, 2023

  • Digital Health Technologies Gaining Ground In Clinical Trials

    Clinical Research News | Growing interest in the use and utility of digital health technologies (DHTs) was on full display at the recent Summit for Clinical Ops Executives. While outsourcing professionals were learning from Merck’s experience in evaluating and selecting DHT suppliers, digital data specialists were getting a progress update on a study comparing sensor-based symptom measures with traditional clinician-rated assessments in patients with early, untreated Parkinson’s Disease.

    Mar 1, 2023

  • Best-Yet Systemic Biomarker Predictor Of Knee Osteoarthritis Progression

    Clinical Research News | Researchers at Duke University have come up with the new “best-in-class” systemic biomarker predictive of clinically relevant knee osteoarthritis that significantly outperforms the top-rated urine test when it comes to recognizing disease progression. Development of the targeted multiple reaction monitoring proteomic panel has been a 12-year labor of love for the team.

    Feb 28, 2023

  • Patient Registries Now Fueling Regulatory Decision-Making

    Clinical Research News | The challenges and opportunities of working with patient registries, one of the most frequently used real-world data types supporting pharmaceutical drug development, was the subject of a series of use cases presented at the recent Summit for Clinical Ops Executives.

    Feb 23, 2023

  • MD Anderson Deploys Technology for Novel Cancer Therapy Research, Personalis and Moderna Evaluate Investigational Personalized Cancer Vaccine, More

    Clinical Research News | A University of California, Davis research team predicts the female response based on input from readily available male clinical trial participants; a new solution enables researchers to measure whole transcriptomes and paired T-cell receptor sequences—alpha and beta chains—in up to 1 million cells; Insilico Medicine receives Orphan Drug Designation from the FDA for a first-in-class small molecule inhibitor designed to treat idiopathic pulmonary fibrosis; and more.

    Feb 23, 2023

  • Pragmatic Trials Testing ‘Passive Digital Marker’ For Detecting Dementia

    Clinical Research News | Research scientists at Indiana University–Purdue University Indianapolis and Regenstrief Institute have developed a “passive digital marker” (PDM), powered by machine learning, to help identify people at risk for Alzheimer’s disease and related dementias at an earlier stage in primary care settings. Application of the PDM will now be tested in the real world in a pair of pragmatic randomized controlled trials.

    Feb 22, 2023

  • AI Transforming Real-World Clinical Development

    Clinical Research News | Artificial intelligence and machine learning solutions bringing tangible improvements to clinical trial conduct took center stage at the recent Summit for Clinical Ops Executives, where a succession of companies—including Pfizer, AbbVie, and IQVIA—took to the podium to share their use cases and road to success.

    Feb 21, 2023

  • Follow the Money: Whole Blood Product Transfuses Soldiers in Active Combat, UC Davis Launches Psychedelics and Neurotherapeutics Research Institute, More

    Clinical Research News | Funding for various metabolomic research advancements, therapeutic developments, and precision medicine applications, a new federally funded research program testing the safety and efficacy of tools for trauma victims with numerous complex injuries, accelerating research across the field of synthetic biology, and more.

    Feb 21, 2023

  • Precision Oncology: Targeting the Ongoing Clinical Staffing Challenges

    Clinical Research News | Recent staffing challenges spurred by the COVID-19 pandemic have played a sustained, negative role in clinical trial workflows. However, through precision technology, healthcare providers can decrease turnover rates and reduce the major ongoing clinical trial workflow challenges resulting from lower personnel.

    Feb 17, 2023

  • A Long Time Coming On Digital Endpoints

    Clinical Research News | Efforts to use digital endpoints to modernize clinical trials have been slowed by an assortment of challenges. But the field will be getting a big push in the right direction in another few months when the first hard evidence will be published demonstrating digital endpoints can live up to their promise of delivering smaller, speedier trials.

    Feb 16, 2023

  • Merck Outlines Structure of Saama Partnership on AI for Clinical Data

    Clinical Research News | AI for clinical data was the subject of several presentations at the recent Summit for Clinical Ops Executives event in Orlando, Fla. SCOPE speakers from across big pharma shared their use cases in applying artificial intelligence and machine learning to various parts of the clinical research process.

    Feb 15, 2023

  • Janssen Redefining Decentralized Clinical Trials With Retail And Mobile Clinics

    Clinical Research News | Janssen Pharmaceuticals (a Johnson & Johnson company) is customizing the way it conducts clinical trials, utilizing retail clinics on their own or with an affiliate healthcare system as well as mobile clinics stationed outside long-term care facilities in the community. This will enable study teams to choose the model that best suits a trial and participants to “choose the adventure” they most prefer.

    Feb 14, 2023

  • Sponsors Asked To Seize The Day On ‘Wisdom Of The Crowd’ Study Solutions

    Clinical Research News | At this week’s Summit for Clinical Ops Executives, Genentech’s Virginia Nido delivered a call to action to her industry peers, asking them to learn the landscape of collaboratively developed clinical trials solutions and start using them.

    Feb 10, 2023

  • SCOPE Awards for Anju, EmVenio, Medidata, StudyKIK, uMotif

    Clinical Research News | ORLANDO—Clinical Research News and ClinEco announced the 2023 SCOPE Best of Show awards yesterday at SCOPE. Products from Anju Software, EmVenio, Medidata, StudyKIK, and uMotif took top honors.

    Feb 9, 2023

  • 2023 Participant Engagement Award Winner Announced

    Clinical Research News | A winner has been chosen for the 7th Annual Participant Engagement Award and was announced after a live presentation and judging session at the Summit for Clinical Ops Executives, on February 6, 2023, in Orlando, Fla.

    Feb 7, 2023

  • Dr. Graham Hatfull on Trialing Bacteriophages for Unprecedented Therapeutic Gains

    Clinical Research News | In the latest episode of the Scope of Things podcast, Graham Hatfull, professor of biological sciences at the University of Pittsburgh, speaks with host Deborah Borfitz about his team’s work to showcase bacteriophages as versatile therapeutic agents.

    Feb 7, 2023

  • uMotif, ActiGraph Announce eCOA/ePRO, Wearable Device Partnership

    Clinical Research News | At the Summit for Clinical Ops Executives—SCOPE—event in Orlando, Fla., this week, uMotif and ActiGraph announced a partnership to make clinical trials more patient-centric and lower burden for participants. The partnership will leverage uMotif’s eCOA/ePRO platform, which streamlines patient engagement and data collection, and ActiGraph's leading expertise in clinical-grade wearable technology.

    Feb 6, 2023

  • A Data-Driven Approach to Clinical Development in Alzheimer’s

    Clinical Research News | In 2020, more than 55 million people lived with dementia. This number is predicted to more than double every twenty years. With the right technology and data science approach, companies can piece together disparate datasets, uncover new insights, and develop therapies to slow the disease.

    Feb 3, 2023

  • To Retain Top Talent, Keep Your Eye On The Ball

    Clinical Research News | Retaining employees despite change factors in and outside the workplace is largely about staying the course with morale-building programs that help people feel supported and their efforts matter. While some level of employee turnover is inevitable, avoiding the spikes may require companywide investment in engaging hired talent to ensure they have the skillset for meeting business goals.

    Feb 2, 2023

  • At AbbVie, Machine Learning Aids Selection Of Clinical Trial Sites

    Clinical Research News | At AbbVie, the introduction of machine learning into the site selection process for clinical studies is reaping tangible returns by increasing the number of sites meeting enrollment and startup time goals by more than 50%. The algorithm helps study teams identify the best sites for a particular trial based on a quantitative analysis of their performance in similar studies done in the past.

    Feb 1, 2023