• Super Agers Initiative Uncovers Biological Mysteries of Longevity, MD Anderson’s Novel Small-Molecule Oncology Therapies Research, More

    Clinical Research News | A newly developed immunotherapy drug that delays the onset of type 1 diabetes in at-risk individuals by an average of almost three years; a study to engineer a human heart model, elucidate fundamental laws of muscular pumps, and apply lessons learned to a cardiovascular bio digital twin model; a highly flexible, modular patent-pending platform and wearable sensor designed to meet the specific needs of clinical trials and remote patient research; and more.

    Nov 30, 2022

  • Follow the Money: Global Digital Therapeutics Clinical Research, Targeted and Minimally Invasive Anti-Cancer Research Platform, More

    Clinical Research News | Funding for clinical-stage urologic oncology pipeline, novel brain cancer research platform, immune microenvironment research of triple-negative breast cancer, and more.

    Nov 29, 2022

  • Pistoia Alliance Works to Mine RWD From Social Media

    Clinical Research News | The Pistoia Alliance has launched a new Community of Experts (CoE) to harness real-world data from social media. The CoE aims to develop best practices and guidelines to use social media analysis as real-world data for patient-focused drug development.

    Nov 22, 2022

  • Vivli To Expand Due To New Data-Sharing Policy Affecting NIH-Funded Research

    Clinical Research News | There is little doubt about the “data magnetism” of Vivli, an open-access, data-sharing platform integrating clinical trial data contributed by biopharmaceutical sponsors, academic institutions, and nonprofit foundations around the world. Vivli was created as a generalist repository in 2018 and since then has driven 126 new research findings—all publicly disclosed, primarily in the peer-reviewed literature.

    Nov 16, 2022

  • Social Determinants Of Health Data Help Identify Sites For Trials

    Clinical Research News | The movement toward decentralized clinical trials isn’t the only emerging trend that could help bump up clinical trial diversity. So, too, could the use of social determinants of health insights to better choose the sites and investigators most likely to enroll underrepresented individuals.

    Nov 15, 2022

  • Five Ways to Minimize Drug Development Costs

    Clinical Research News | The worldwide population is aging, and the prevalence of many diseases is on the rise, making rapid drug discovery and approval ever more critical. However, the cost of bringing a new drug to market is substantial. Using newer technologies, drug companies may be able to reduce costs associated with development and ultimately enhance their odds of successful approvals by improving the efficiency of clinical trials.

    Nov 11, 2022

  • Open-Source Platform Matches Cancer Patients to Precision Medicine Trials

    Clinical Research News | An open-source computer platform developed at Dana-Farber Cancer Institute is adding ease and speed to the process of matching cancer patients to trials of therapies targeting genomic alterations. The matching tool, which links individual clinical and genomic information to trial eligibility data in real time, is designed to help overcome the stubbornly low precision medicine trial participation rate despite more common use of genomic profiling.

    Nov 9, 2022

  • Walmart Commits To Increasing Access To Clinical Research

    Clinical Research News | With the launch of Walmart Healthcare Research Institute earlier this month, the retail giant is doubling down on its efforts to be a healthcare destination for the masses. The aim is to make clinical research “equitable for all,” including people living in rural communities who have less access to trials than people in cities with an academic center nearby.

    Nov 3, 2022

  • Strep A Surveillance Protocols To Accelerate Vaccine Development Efforts

    Clinical Research News | Best practice surveillance protocols for seven diseases caused by group A Streptococcus (strep A) were recently released, and public health researchers are now actively working to identify several key sentinel sites to implement them. Harmonizing case definitions and the surveillance methodologies is a key step in accelerating development of a safe, effective, and affordable strep A vaccine to prevent these diseases.

    Nov 2, 2022

  • Janssen’s Jason LaRoche on Reducing Greenhouse Gas Emissions and the Environmental Impact of Clinical Trials

    Clinical Research News | Various stakeholders across the clinical trial enterprise are launching an initiative to reduce the environmental impact of clinical research. Jason LaRoche, Director of Clinical Innovation at Janssen Pharmaceuticals, stands at the helm of this ambitious project, aiming to quantify clinical trial greenhouse gas emissions and drastically reduce the adverse downstream effects of research operations.

    Nov 1, 2022

  • Walgreens Launches Europe’s Only Oncology Radiology Platform, New Mandates Include HIV Patients in TB Trials, More

    Clinical Research News | A new application that enables real-time data access for sponsors and clinical research sites; a first-of-its-kind solution for aggregating, cleaning, and transforming clinical data; two new applications to help clinical teams improve site selection and optimize trial design; and more.

    Oct 27, 2022

  • Follow the Money: Nerve Research for Cardiovascular and Digestive Disorders, NIHR Initiative for HIV and Other Diseases, More

    Clinical Research News | Funding for biomedical research through high-performance computing, comparative clinical effectiveness research to reduce inequities in maternal health care and outcomes, identifying vulnerabilities in pediatric cancers, and more.

    Oct 26, 2022

  • FDA Guidance Could Help Standardize Eligibility Criteria For Lung Cancer Trials

    Clinical Research News | For patients with lung cancer, meeting the eligibility criteria for clinical trials has been a major roadblock to their participation. Over time, studies have grown more complex and expensive and sponsors, eager to optimize the scientific yield of a trial, have become incredibly strict about who meets the enrollment requirements.

    Oct 20, 2022

  • Clinical Trials At The Intersection With Healthcare

    Clinical Research News | Digitalization and the changing regulatory landscape, shared space between routine clinical care and research, the increased complexity of clinical trials in decentralized settings, and practical challenges in providing patient-centric solutions were the focal points of a plenary keynote panel discussion at the recent Summit for Clinical Ops Executives Europe (SCOPE Europe) in Barcelona, Spain.

    Oct 18, 2022

  • When Kids Can Assent To Trial Participation, It Gets Complicated

    Clinical Research News | Experts recently gathered at a bioethics symposium on ethical considerations in research for pediatric populations, hosted by the New York Academy of Sciences, for a panel discussion focused on parental permission and children capable of assenting to participation.

    Oct 13, 2022

  • Digital Strategies For Optimizing Clinical Development

    Clinical Research News | When it comes to balancing the need for high-quality data collection and patient-centric strategies for engaging study participants, hybrid clinical trials utilizing wearable devices and other digital health tools can be challenging to conduct. But when carefully crafted, a digital strategy can also help accelerate trials, improve diversity in recruitment, and improve outcomes for participants.

    Oct 12, 2022

  • Assent Process For Pediatric Trials An ‘Experiment For All Of Us’

    Clinical Research News | Despite regulatory and congressional efforts to protect human research subjects that date back 75 years, ethical dilemmas concerning the participation of pediatric populations in clinical trials persist with no consensus on several key issues—among them the age at which children are too young to understand what they’re agreeing to, and how to respect nonverbal expressions of dissent.

    Oct 11, 2022

  • Select European Research Institutes Become the First to Join International Data Network

    Clinical Research News | Research institutes representing five western European countries—Finland, Germany, Norway, Spain, and Sweden—will become the first to join the Federated European Genome-phenome Archive, an international distributed data network designed to share highly-sensitive human ’omics data internationally.

    Oct 6, 2022

  • University College London’s Dr. Anna David on Increasing the Representation of Pregnant Patients in Clinical Trials

    Clinical Research News | University College London’s Dr. Anna David speaks about the obstacles facing pregnant patients in today’s medical landscape and the past and present strides made to increase their representation in clinical research, all in the latest episode of the Scope of Things podcast.

    Oct 4, 2022

  • Finding More Patients for Clinical Trials by Unlocking Intelligence from Patient Records

    Clinical Research News | Novel artificial intelligence methods have recently been proven clinically valid and valuable for capturing target patient populations investigated by a clinical trial. The intelligence and outputs from novel AI methods benefit clinicians by enabling an ecosystem based on knowledge discovery and sharing in a privacy-preserving manner.

    Sep 30, 2022