• Walgreens, Freenome Team Up, New AI Products from ObjectiveHealth, Saama, More

    Clinical Research News | Walgreens and Freenome team up to advance clinical studies; ObjectiveHealth announces new AI tool to optimize clinical trial performance; Saama deploys AI solutions to automate key clinical development processes; American Gene Technologies launch new company that solely focuses on HIV cure research; and more.

    Jun 29, 2023

  • Budget Proposals For Industry-Sponsored Pediatric Trials Need Renegotiating

    Clinical Research News | Many sites engaged in industry-sponsored pediatric clinical trials are struggling to make them monetarily feasible because sponsors often apply the same budget figures used for adult trials and sites may be unaccustomed to talking about line-item costs for different procedures.

    Jun 28, 2023

  • Follow the Money: AI Drug Treatments, Stocks, Quantum Metabolic Polarizers, More

    Clinical Research News | Leveraging AI for drug treatments, stock investments, revolutionizing metabolic MRIs with polarizers, and more.

    Jun 27, 2023

  • Success in Simplicity: Complex Clinical Trials and the eCOA Systems That Support Them

    Clinical Research News | It’s no coincidence that clinical trials are becoming more complex. Advancements in technology are enabling sponsors, clinicians, and trial teams to gather more information than ever before. However, the latest “bells and whistles” can add complexity to trials and distract trial teams from their main focus: collecting data to advance therapies for very ill patients who need them most.

    Jun 23, 2023

  • Biologics, Anti-Inflammatory Drugs Current Focus Of Alzheimer’s Disease Trials

    Clinical Research News | The latest report on clinical trials in the Alzheimer’s drug development pipeline points to the growing potential of anti-amyloid monoclonal antibodies for treating the brain-robbing condition. Anti-inflammatory agents comprise the single largest therapeutic category with 25 drugs, but astoundingly no two are aimed at the same target.

    Jun 21, 2023

  • Rescuing a Study in Jeopardy with Comprehensive Clinical Adjudication

    Clinical Research News | Global clinical trial programs are complex, often encompassing dozens of studies for increasingly uncommon indications. Sponsors of these programs are wisely seeking out independent adjudication of clinical events, or endpoints, that occur over the course of the trial to ensure patient safety and the efficacy of drugs and devices. While endpoint adjudication is not required by regulatory bodies, it can deliver valuable insights during a trial and lend strong, unbiased support for approvals down the road.

    Jun 16, 2023

  • N-Lorem Foundation Bringing Real Hope To ‘N-Of-1’ Patients

    Clinical Research News | Stanley T. Crooke, M.D., Ph.D., founder and longtime leader of the company that pioneered RNA-targeted therapeutics, is now chairman and CEO of the n-Lorem Foundation descaling the technology to treat patients helpless before a healthcare system that wasn’t built for “n-of-1” problems. He will be addressing a room of physicians and scientists tomorrow on the campus of Vanderbilt University.

    Jun 14, 2023

  • Novo Nordisk Home-Grows Group To Digitalize Early Clinical Research

    Clinical Research News | Novo Nordisk launched a digital science and innovation group early in 2022 with the intention of digitalizing clinical research activities, mirroring the way the commercial side of the house has been operating for years. Novo Nordisk has embedded the group within the research organization rather than created a separate product or short-lived initiative.

    Jun 14, 2023

  • Capsule-Sized Device Permits Noninvasive Exploration Of Small Intestine

    Clinical Research News | An international team of researchers has completed preliminary testing of a swallowable device for collecting samples from people under standard, day-to-day conditions to better understand what is happening inside their small intestine. The lengthy organ has up to how been inaccessible unless individuals first fasted and were sedated.

    Jun 8, 2023

  • Predicting Knee Osteoarthritis Progression: Proteomics, Biomarkers, and the Future of Treatment

    Clinical Research News | What if you could predict the progression of knee osteoarthritis through a simple blood test? That’s the vision of Dr. Virginia Byers Kraus, a professor at Duke University School of Medicine. Knee osteoarthritis (OA) affects 60 million adults in the US and projected to increase to 78 million by 2040, yet we don’t currently have very sensitive tools for diagnosis or disease-modifying drugs or treatments.

    Jun 6, 2023

  • Diversity—And Science—Could Benefit From 90-Year-Old Research Approach

    Clinical Research News | After embracing a research approach long used in the public health field, neuroscience investigators at the University of California, Riverside, (UCR) made some surprising discoveries about the Latino community—including the cultural realities driving conduct problems in preadolescent girls.

    Jun 1, 2023

  • Follow the Money: Health Equity Research, Clinical AI, Telehealth, More

    Clinical Research News | PCORI funding opportunities for comparative clinical effectiveness research; Carolina consortium gets NIH funding for health equity research, funding to grow Southeast Asia’s largest telehealth platform; more.

    May 30, 2023

  • Realizing The Benefits Of Bringing The Trial To The Patient

    Clinical Research News | During the worst days of the COVID-19 pandemic, drug sponsors, clinical sites, and patients alike discovered the value of in-home services in allowing research studies to proceed while minimizing patients’ potential exposure to the virus from on-site visits. Such services were a lifeline to the research industry. Today, in-home services are being baked into trial protocols not out of dire necessity, but rather out of an appreciation for their value in supporting patient-centric trials with decentralised components.

    May 26, 2023

  • News and Products from Trialbee, Flatiron, Sanofi, Phesi, Personalis, More

    Clinical Research News | Trialbee enhances recruitment strategy; Flatiron and Sanofi set out to redesign the clinical trial experience for sponsors, sites, and patients; and Phesi has published the first edition of its Digital Patient Profile (DPP) catalog. Plus: partnerships for Culmination Bio, Cofactor Genomics, Personalis, Ono Pharmaceuticals, National Cancer Center, and more.

    May 24, 2023

  • As CVS Slowly Exits Clinical Trial Business, Walgreens Continues Ramp-Up

    Clinical Research News | Last week, CVS Health announced its intension to phase out of the clinical trial business with a full exit expected by the end of 2024. In a conversation with Clinical Research News, Walgreens Chief Clinical Trials Officer Ramita Tandon applauds her colleagues at CVS for being the first mover. She is also reassuring Walgreens stakeholders that “we are not going away.”

    May 23, 2023

  • New Antimicrobial Susceptibility Test Suggests Generic Z-Pak Can Cure Superbugs

    Clinical Research News | A new antimicrobial susceptibility testing (AST) method developed by scientists at the University of California, Santa Barbara, resolves the longstanding conflict between what the gold-standard assay says will work and actual patient outcomes when it comes to selecting antibiotics. The alternative AST protocol reveals that antibiotics already widely available on the market can cure superbugs.

    May 18, 2023

  • Blinded, Randomized Clinical Trial Suggests AI ‘Near-Ready For Prime Time’

    Clinical Research News | In a first-of-its-kind, blinded and randomized clinical trial of artificial intelligence (AI) in cardiology, investigators at Cedars-Sinai Medical Center have shown that an “AI assistant” for assessing heart health works even better than sonographers at reading echocardiograms. The software was integrated with the institution’s picture archiving and communication system that securely stores and digitally transmits electronic images.

    May 16, 2023

  • Data Matters: Creating the Perfect Health Research Cohort

    Clinical Research News | Research scientists know that an important foundation of research is cohort creation; many critical decisions are made based on how the cohort is built and designed. Better cohort creation can lead to more accurate findings and better care outcomes. But how do you build a better cohort? It all starts with the research question and the data at hand.

    May 12, 2023

  • Parkinson’s Disease Trials Need Better Markers Of Cognitive Changes

    Clinical Research News | The instruments commonly used to assess cognitive decline in Parkinson’s disease (PD) patients enrolled in neuroprotective clinical trials are “poorly suited to the task,” according to industry consultant Travis Turner, Ph.D., assistant professor and director of the neuropsychology division at Medical University of South Carolina, and senior clinical director for movement disorders at WCG. “I strongly suspect that good interventions have been discarded because [of] the tests that were trying to measure efficacy.”

    May 10, 2023

  • Predictive Analytics Giving The Lowdown on Clinical Trial Performance

    Clinical Research News | A data-agnostic integration platform for optimizing trial planning and conduct hit the streets three years ago, bringing near-real-time insights about every participant, site, country, region, and study to companies struggling to reduce the cost and speed the pace of clinical research. The technology, powered by machine learning, is currently underpinned by data from more than 2,000 trials and over 400,000 healthcare providers.

    May 9, 2023