• New Patient Scoring Method To Enable Precision Medicine For Chronic Diseases

    Clinical Research News | In a big advance for precision medicine, researchers in Australia have developed a genetic biomarker of people’s response to sodium reduction. It is often but not always the case that modifying sodium levels lowers blood pressure by reducing the fluid volume of blood in the cardiovascular system, and knowing in advance how patients will respond could help eliminate the “treatment odyssey” that many of them are experiencing.

    Feb 8, 2024

  • Best of Show Finalists Named for SCOPE 2024

    Clinical Research News | Dozens of companies are showcasing new products at next week’s Summit for Clinical Ops Executives, and 37 have been named finalists in the Best of Show People’s Choice Awards. The SCOPE community is invited to identify exceptional innovation in technologies used by life science professionals, voting on the most impactful new products of the year. Winners will be announced at the event on Tuesday, February 13.

    Feb 7, 2024

  • Two-In-One Cholesterol-Lowering Vaccine Now Ready For Clinical Testing

    Clinical Research News | Investigators with The University of New Mexico (UNM) and the National Institutes of Health (NIH) have succeeded in developing a cholesterol-lowering vaccine that works independently of statins. It could become the next vaccine-based approach targeting PCSK9 (proprotein convertase subtilisin/kexin type 9 serine protease) to enter clinical trials.

    Feb 6, 2024

  • Greenphire Acquires Clincierge

    Clinical Research News | Yesterday, Greenphire, an innovator in clinical trials software, announced the acquisition of Clincierge, a premier provider of concierge travel and logistics support for patients participating in clinical trials.

    Feb 2, 2024

  • Smartwatch Could Reduce Fallout From False-Positive AFib Readouts

    Clinical Research News | A clinical-grade smartwatch does a good job of detecting possible atrial fibrillation (AFib), which could fill the need for a noninvasive option for monitoring patients for more than 30 days. Current available electrocardiography (ECG) technologies, such as Holter monitors and wearable event recorders, are both more time-limited and resource-intensive.

    Feb 1, 2024

  • Illumina Ventures Labs Now Operational, Personalized Medicine Coalition Releases 2024 Plans, Imagine Pharma Forms the Imagine Pharma Foundation, Collaborations, More

    Diagnostics World | Illumina Ventures Labs is now operational and finalizing agreements with several startup companies; the Personalized Medicine Coalition has released their Strategic Plan for Advancing Personalized Medicine in 2024; Imagine Pharma announced the formation of The Imagine Pharma Foundation, a private not for profit charitable organization dedicated to advancing metabolic research to significantly impact the lives of those affected by diabetes, with a particular emphasis on serving veterans; several collaborations and partnerships have been formed to tackle trials, studies, and research; more.

    Jan 31, 2024

  • Follow the Money: Most Extensive Liver Cirrhosis Study Funded, Expanded Biomedical Research Program, Antibody Development, More

    Clinical Research News | Newcastle University, University of Edinburgh, and Boehringer Ingelheim have received funding to begin the most extensive clinical study into liver cirrhosis ever; the University of New England has received an award from the National Institutes of Health to support an Institutional Development Award Center of Biomedical Research Excellence to be named the UNE Center for Cell Signaling Research; Oxitope Pharma and Arxx Therapeutics have merged to form Calluna Pharma Inc. (Calluna) and intend to work on a pipeline of selective antibodies that target inflammatory and fibrotic indications; more.

    Jan 30, 2024

  • Living Biobank Of Brain Metastasis Samples Enabling ‘Personalized Medicine 2.0’

    Clinical Research News | Researchers at the CNIO (Spanish National Cancer Research Centre) are forwarding the idea that metastasis, rather than the primary tumor, should be the focus of cancer treatment, which would both further the cause of personalized medicine and generate biomarkers of sensitivity or resistance to specific drugs.

    Jan 24, 2024

  • AI-Based Platform For Detecting AFib Put To The Test In VA Facilities

    Clinical Research News | Investigators at Cedars-Sinai Medical Center are looking to minimize the biases in the data used by artificial intelligence (AI) algorithms, most recently a deep learning model trained on nearly a million electrocardiograms (ECGs) to identify people with abnormal heart rhythms. The inputs came from a pair of large Veterans Affairs (VA) hospital networks serving a highly diverse set of patients in terms of demographics and comorbidities.

    Jan 23, 2024

  • Automation Accelerates and Reduces Inconsistencies in Drug Development

    Clinical Research News | New drugs can take over a decade to receive approval. While drug development cannot be rushed, advancements in AI and automation can help life sciences organizations ensure shorter timelines to market, enhanced patient safety, and maximal resource utility.

    Jan 19, 2024

  • Digital Endpoints: Trends and Opportunities in Drug Development and Beyond

    Clinical Research News | When the Digital Medicine Society (DiMe) launched its Library of Digital Endpoints, a listing of industry-sponsored studies of new medical products or applications that use sensor-derived endpoints, there were a total of 35. Four years later, that same library now includes over 400 unique digital endpoints collected by over 60 sponsors to answer questions about the efficacy of new medical products.

    Jan 17, 2024

  • Alzheimer’s Disease Prevention Trials Require ‘More Than Science’

    Clinical Research News | Things could start looking up for randomized controlled clinical trials (RCTs) in Alzheimer’s disease (AD) prevention, which have a 25-year track record of failure, once broad biomarkers of the brain-robbing condition are found that reflect real-life risk factors.

    Jan 16, 2024

  • The Last Mile In Preventing A Deadly Hospital Infection

    Clinical Research News | The “power of the team approach” was on full display for a study designed to understand the contribution of asymptomatic carriers to the spread of Clostridioides difficile in hospitals.

    Jan 10, 2024

  • Brain Health Equity Will Take A ‘Slow-Cooking’ Approach To Alzheimer's Trials

    Clinical Research News | The “power of the team approach” was on full display for a study designed to understand the contribution of asymptomatic carriers to the spread of Clostridioides difficile in hospitals.

    Jan 9, 2024

  • Practical Considerations for Managing Cell and Gene Therapy Supply Chains

    Clinical Research News | Cell and gene therapies (CGT) have made substantial progress in recent years thanks to several breakthroughs and higher flow of funds into the space. Despite this progress, the challenges of working with living therapies remain highly complex, risk-laden, and time-consuming.

    Jan 5, 2024

  • Top Stories from 2023: CVS, Walgreens, CROs in Trial Management, Decentralized Models, More

    Clinical Research News | Last year was full of growing pains for clinical research as decentralized trial models continued to mature, AI took a more aggressive role in study planning and execution, and the player landscape continued to shake out. Here are the top stories from Clinical Research News as well as thought leaders in the industry

    Jan 4, 2024

  • Trendspotting: What’s Coming for Clinical Trials and Research in 2024

    Clinical Research News | We spoke with leaders and experts in the Clinical Research community about their predictions for 2024.

    Jan 3, 2024

  • Medidata Launches Research Alliance, BC Platforms Acquires Medexprim, Expansions, New Platforms, More

    Clinical Research News | Medidata has launched the Medidata Research Alliance; BC Platforms has acquired Medexprim, a leading European real-world data company; Velocity Clinical Research has expanded into Poland and acquired its first site, ClinMedica Research; and more.

    Dec 28, 2023

  • Follow the Money: PCORI Approves Awards For Multiple CER Studies, Advancing Women’s Reproductive Immunotherapies, Collaborations, More

    Clinical Research News | The Patient-Centered Outcomes Research Institute (PCORI) approves funding awards to support 20 new patient-centered comparative clinical effectiveness research (CER) studies; Freya Biosciences intends to advance the clinical development of its lead drug candidate; Sanofi enters a multi-year research collaboration with French pharmatech company Aqemia; and more.

    Dec 27, 2023

  • Smart Packaging Delivers Medication Adherence Insights At Pizza-Delivery Speed

    Clinical Research News | Medication adherence in phase 2 and phase 3 clinical trials is far less perfect than the 98% often cited in peer-reviewed published papers on those studies. While solutions to address it exist in the form of smart packaging, the will to adopt such technologies has been tepid, leading to widespread overdosing of trial participants—most notably those who take the drug as instructed—and, ultimately, directions for use on drug labels and unnecessary side effects once the drug hits the market.

    Dec 20, 2023