• Massive Acquisition Of Obesity Drug Developer, Clinical Programs For Rare Genetic Disease, Clinical Translation Of Gene Therapies, More

    Clinical Research News | Novo Nordisk acquires Inversago Pharma and the development of an appetite regulator; ADARx Pharmaceuticals will advance clinical programs on a rare genetic disease with new funding; Kriya Therapeutics plans to use Series C funding for clinical translation of gene therapies; more.

    Aug 30, 2023

  • AI-Powered inClinico Aims To Solve The Phase 2-To-3 Transition Problem

    Clinical Research News | Insilico Medicine recently broke the news that one of its platforms, powered by artificial intelligence (AI), succeeded in predicting the outcomes of several phase 2 clinical trials.

    Aug 24, 2023

  • Novel Biomarker Tracks Tightly With Tau Tangles In Alzheimer’s Disease

    Clinical Research News | Researchers in the U.S. and Sweden have identified a biomarker (MTBR-tau243) for Alzheimer’s disease that tracks with the amount of damaging tau tangles in the brain and, when combined with a specific phosphorylated tau species (p-tau205), is nearly as predictive of cognitive function as tau-positron emission tomography (tau-PET) imaging.

    Aug 23, 2023

  • ‘Swarm Learning’ Approach To Improving Care Of Colorectal Cancer Patients

    Clinical Research News | Over the next three years, researchers from across five universities in Germany will be using “swarm learning” on retrospective tissue samples to gain insights on the tumor biology of hereditary colorectal cancer (CRC).

    Aug 22, 2023

  • Toward Optimizing Site Feasibility Assessment For Clinical Trials

    Clinical Research News | Selecting appropriate sites is one of the most crucial factors for determining successful completion of a clinical trial. It is important to ensure that potential trial sites have the capability to meet the protocol requirements and the capacity to deliver the study objectives in a safe and efficient manner.

    Aug 18, 2023

  • Neurosurgeons In Czech Republic Test Writing Capabilities Of ChatGPT

    Clinical Research News | Researchers in the Czech Republic succeeded in using ChatGPT (Chat Generative Pre-trained Transformer) to produce a convincing scientific article in only one hour with no special human training—a feat intended to point out the current capabilities of large language models (LLMs).

    Aug 16, 2023

  • AI Bringing Major Change To The Way Studies Get Conducted

    Clinical Research News | Clinical research stakeholders, most especially study sponsors, are now firmly onboard with the idea of using artificial intelligence (AI) to improve the conduct of clinical trials.

    Aug 15, 2023

  • Proteins In The Blood Hint At Biological Basis Of Long COVID

    Clinical Research News | A point-of-care (POC) diagnostic test for long COVID is under development that would be a godsend to the millions of Americans still suffering the health consequences of SARS-CoV-2 months after being infected.

    Aug 11, 2023

  • Ramita Tandon and How Walgreens Is Tackling Disparities in Clinical Trials

    Clinical Research News | The COVID-19 pandemic amplified a lot of existing weaknesses in the healthcare system, and clinical research was no exception: less than 5% of the nation partakes in clinical trials and 75% of those participants are white. This disparity indicates that drugs undergoing clinical trials don’t necessarily have the same effect on the rest of the American population, particularly those from ethnic and racial minority groups.

    Aug 8, 2023

  • Three Keys to Improving Diversity in Clinical Trials

    Clinical Research News | Clinical research should be a viable option for everyone who wishes to participate. Sponsors know that diverse trials lead to stronger data and better drugs, yet there are many obstacles to recruiting and retaining diverse participants – from distrust, to lack of access, to financial and logistical barriers.

    Aug 4, 2023

  • Researchers Close In On Protein Panel For Predicting Islet Autoimmunity

    Clinical Research News | A team of researchers from North America and Europe have identified a panel of 83 markers in the blood of children genetically predisposed to develop type 1 diabetes that looks promising as a predictor of which individuals will progress to islet autoimmunity six months prior to its onset.

    Aug 3, 2023

  • Mitigating Tactics To Improve The Generalizability Of Pragmatic Trials

    Clinical Research News | Randomized controlled trials are a fantastic first step in assessing the clinical effects of medical interventions, but they are not sufficient to transform the “busy throughput environment” of real-world healthcare involving appointment scheduling and referrals, differing practice patterns, and patients with comorbidities and social determinants of health like housing instability and low literacy skills.

    Aug 1, 2023

  • Crowd-Sourced Neuroscience, New Sickle Cell Dataset Published, FDA-Approved Software

    Clinical Research News | Researchers from around the world are invited to publicly design a shared brain experiment that will run on the Allen Brain Observatory, Angry@Arthritis has announced the first global osteoarthritis clinical trial locator, Indiana Sickle Cell Data Collection program published a paper on persons living with the disease in the state, and Boston Scientific received FDA approval to new software. Plus, new product updates and partnerships from Arrayjet, Critical Path Institute, Clinisys, and more.

    Jul 27, 2023

  • Follow the Money: AI Platform for Acute Immune States, Acquisitions, Expanding Solutions Portfolio

    Clinical Research News | AI platform used for acute immune states, acquisitions, solutions portfolio expansion, and more.

    Jul 26, 2023

  • The Role of Digital Transformation in Patient Engagement, Recruitment, & Retention

    Clinical Research News | Researchers at the Laureate Institute for Brain Research (Tulsa, Oklahoma) are repurposing a vibrating capsule that is FDA-cleared for treating chronic constipation to study how people sense the hidden signals originating in their gastrointestinal (GI) system.

    Jul 21, 2023

  • Vibrating Capsule Repurposed For Assessment of ‘Visceral Acuity’

    Clinical Research News | Researchers at the Laureate Institute for Brain Research (Tulsa, Oklahoma) are repurposing a vibrating capsule that is FDA-cleared for treating chronic constipation to study how people sense the hidden signals originating in their gastrointestinal (GI) system.

    Jul 19, 2023

  • Custom-Designed Vaccines Look Promising For Treating Melanoma

    Clinical Research News | Messenger RNA (mRNA) vaccines “personalized” to the genetics of a tumor look promising for improving the treatment of melanomas, based on results of a phase 2 clinical trial recently presented at the American Society of Oncology congress in Chicago.

    Jul 18, 2023

  • CROs Leading The Way In Modern-Day Clinical Data Management

    Clinical Research News | Contract research organizations (CROs) increasingly find themselves on the leading edge of changes afoot in clinical data management, making it less about the policing of information and more about extracting meaningful insights from it.

    Jul 13, 2023

  • Murray Aitken on Advancing Diversity in Clinical Development

    Clinical Research News | Diversity in clinical trials plays a key role in determining the effectiveness of new medications and treatments. However, clinical trials have proven that participant pools are not as diverse as they should be.

    Jul 11, 2023

  • Time Is Now To Take A Hard Look At Decentralized Trials

    Clinical Research News | Many assumptions have been made about how decentralized clinical trials (DCTs) could help with clinical trial diversity although little “rigorous evidence” exists regarding actual effects on study enrollment.

    Jul 6, 2023