• Adopting New Patient-Centric Payment Solutions for Whole-Industry Benefits

    Clinical Research News | The clinical trial landscape has a long-acknowledged problem – a lack of participant diversity. Most clinical trial participants are from higher-income households, white and male.

    Sep 22, 2023

  • COVID Vaccine Developers May Want To Pivot To Symptom Prevention

    Clinical Research News | Vaccine developers may want to consider designing formulations intended to prevent symptoms rather than infection, which the COVID-19 pandemic has demonstrated can be hard to do with any long-lasting effect.

    Sep 19, 2023

  • City of Hope’s Harmonized, Findable, Accessible Precision Medicine Data Platform

    Clinical Research News | INNOVATIVE PRACTICES AWARDS—When City of Hope wanted to better use its primary and secondary clinical research data and harmonize files on more than 700,000 patients so they were findable and accessible, the hospital built a highly scalable, compliant cloud-based platform.

    Sep 14, 2023

  • Changes Afoot In The Regulatory Landscape For Companion Diagnostics

    Clinical Research News | The U.S. Food and Drug Administration (FDA) has been making moves signaling its intention to better align the regulatory framework for companion diagnostics (CDx) to what is happening in real-world clinical practice.

    Sep 13, 2023

  • Study Finds Breast Cancer Spreads During Sleep, Highlights Role Of Hormones

    Clinical Research News | The recent discovery that the metastatic spread of breast cancer accelerates during sleep sparked a lively conversation at last month’s Next Generation Dx Summit about new paths of exploration for thwarting a deadly pan-cancer process claiming 12 lives worldwide every minute.

    Sep 12, 2023

  • Automated Speech Analysis: A Promising New Avenue For Patient Monitoring In Alzheimer’s Trials

    Clinical Research News | As experimental drugs to treat Alzheimer’s disease increasingly target the disease’s very initial stages, monitoring the impact of novel treatments on cognition has become a complex undertaking for trial sponsors.

    Sep 8, 2023

  • The Clinical Realities Of Chronic Wounds With Dr. Caroline Fife

    Clinical Research News | When Dr. Caroline Fife stepped into her first clinical trial in 1997, she was met with a waiting room packed with patients. Despite the large number of potential participants, none of them were considered healthy enough for the clinical trial. That was when she realized something was very wrong.

    Sep 5, 2023

  • Phastar Appoints New CEO, New Global Research Centers, New Partnerships Announced, More

    Clinical Research News | Phastar appoints a new CEO amid organization changes and growth plans; Celltrion opens a Global R&D Center in South Korea for research capabilities and technologies spanning all areas of biopharmaceutics; Clario and AliveCor, Standigm and Nashville Biosciences, C2i Genomics and the Tel Aviv Sourasky Medical Center (Ichilov) announce partnerships; more.

    Aug 31, 2023

  • Massive Acquisition Of Obesity Drug Developer, Clinical Programs For Rare Genetic Disease, Clinical Translation Of Gene Therapies, More

    Clinical Research News | Novo Nordisk acquires Inversago Pharma and the development of an appetite regulator; ADARx Pharmaceuticals will advance clinical programs on a rare genetic disease with new funding; Kriya Therapeutics plans to use Series C funding for clinical translation of gene therapies; more.

    Aug 30, 2023

  • AI-Powered inClinico Aims To Solve The Phase 2-To-3 Transition Problem

    Clinical Research News | Insilico Medicine recently broke the news that one of its platforms, powered by artificial intelligence (AI), succeeded in predicting the outcomes of several phase 2 clinical trials.

    Aug 24, 2023

  • Novel Biomarker Tracks Tightly With Tau Tangles In Alzheimer’s Disease

    Clinical Research News | Researchers in the U.S. and Sweden have identified a biomarker (MTBR-tau243) for Alzheimer’s disease that tracks with the amount of damaging tau tangles in the brain and, when combined with a specific phosphorylated tau species (p-tau205), is nearly as predictive of cognitive function as tau-positron emission tomography (tau-PET) imaging.

    Aug 23, 2023

  • ‘Swarm Learning’ Approach To Improving Care Of Colorectal Cancer Patients

    Clinical Research News | Over the next three years, researchers from across five universities in Germany will be using “swarm learning” on retrospective tissue samples to gain insights on the tumor biology of hereditary colorectal cancer (CRC).

    Aug 22, 2023

  • Toward Optimizing Site Feasibility Assessment For Clinical Trials

    Clinical Research News | Selecting appropriate sites is one of the most crucial factors for determining successful completion of a clinical trial. It is important to ensure that potential trial sites have the capability to meet the protocol requirements and the capacity to deliver the study objectives in a safe and efficient manner.

    Aug 18, 2023

  • Neurosurgeons In Czech Republic Test Writing Capabilities Of ChatGPT

    Clinical Research News | Researchers in the Czech Republic succeeded in using ChatGPT (Chat Generative Pre-trained Transformer) to produce a convincing scientific article in only one hour with no special human training—a feat intended to point out the current capabilities of large language models (LLMs).

    Aug 16, 2023

  • AI Bringing Major Change To The Way Studies Get Conducted

    Clinical Research News | Clinical research stakeholders, most especially study sponsors, are now firmly onboard with the idea of using artificial intelligence (AI) to improve the conduct of clinical trials.

    Aug 15, 2023

  • Proteins In The Blood Hint At Biological Basis Of Long COVID

    Clinical Research News | A point-of-care (POC) diagnostic test for long COVID is under development that would be a godsend to the millions of Americans still suffering the health consequences of SARS-CoV-2 months after being infected.

    Aug 11, 2023

  • Ramita Tandon and How Walgreens Is Tackling Disparities in Clinical Trials

    Clinical Research News | The COVID-19 pandemic amplified a lot of existing weaknesses in the healthcare system, and clinical research was no exception: less than 5% of the nation partakes in clinical trials and 75% of those participants are white. This disparity indicates that drugs undergoing clinical trials don’t necessarily have the same effect on the rest of the American population, particularly those from ethnic and racial minority groups.

    Aug 8, 2023

  • Three Keys to Improving Diversity in Clinical Trials

    Clinical Research News | Clinical research should be a viable option for everyone who wishes to participate. Sponsors know that diverse trials lead to stronger data and better drugs, yet there are many obstacles to recruiting and retaining diverse participants – from distrust, to lack of access, to financial and logistical barriers.

    Aug 4, 2023

  • Researchers Close In On Protein Panel For Predicting Islet Autoimmunity

    Clinical Research News | A team of researchers from North America and Europe have identified a panel of 83 markers in the blood of children genetically predisposed to develop type 1 diabetes that looks promising as a predictor of which individuals will progress to islet autoimmunity six months prior to its onset.

    Aug 3, 2023

  • Mitigating Tactics To Improve The Generalizability Of Pragmatic Trials

    Clinical Research News | Randomized controlled trials are a fantastic first step in assessing the clinical effects of medical interventions, but they are not sufficient to transform the “busy throughput environment” of real-world healthcare involving appointment scheduling and referrals, differing practice patterns, and patients with comorbidities and social determinants of health like housing instability and low literacy skills.

    Aug 1, 2023